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Related to adrenocorticotrophic hormone: Adrenocorticotropic Hormone Test, follicle stimulating hormone, Adrenocorticotropic hormone deficiency
ACTHA 39-amino acid hormone produced by the anterior pituitary gland, which regulates adrenocortical activity, stimulating release of cortisol, mineralocorticoids, and adrenal androgens; pituitary ACTH is regulated by corticotropin-releasing hormone (CRH).
Daily pattern ACTH levels vary over the space of a 24-hour day, peaking at 6–8 am and evening 6–11 pm; ACTH suppression or stimulation testing may be required to confirm the diagnosis of changes in adrenal function.
ACTH increased in Addison’s disease, congenital adrenal hyperplasia, Cushing disease, pituitary-dependent Cushing syndrome, ectopic ACTH-producing tumours, Nelson syndrome.
ACTH decreased in Secondary adrenocortical insufficiency, adrenal carcinoma, adenoma.
Ref range < 120 pg/mL
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
ad·re·no·cor·ti·co·tro·phic hor·mone(ă-drēnō-kōŕti-kō-trōfik hōŕmōn)
Pituitary hormone that serves to stimulate the growth and nutrition of the suprarenal gland.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012