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having a stimulating effect on the adrenal cortex; called also adrenocorticotrophic and corticotropic.


, adrenocorticotrophic (ă-drē'nō-kōr'ti-kō-trō'pik, -trō'fik),
Stimulating growth of the suprarenal cortex or secretion of its hormones.
[adrenal cortex + G. trophē, nurture; tropē, a turning]


/adre·no·cor·ti·co·tro·phic/ (-kor″tĭ-ko-tro´fik) adrenocorticotropic.


adjective Referring to the adrenal cortex.


Causing stimulation of the outer layer of the adrenal gland and promoting secretion of the adrenal cortical hormones.


, adrenocorticotrophic (ă-drē'nō-kōr'ti-kō-trō'pik, -trō'fik)
Stimulating growth of the suprarenal cortex or secretion of its hormones.
Synonym(s): adrenotropic, adrenotrophic.
[adrenal cortex + G. trophē, nurture; tropē, a turning]


adrenocorticotropic; corticotropic.

adrenocorticotrophic hormone
a hormone elaborated by the anterior lobe of the pituitary gland that stimulates the action of the adrenal cortex. See also acth.
adrenocorticotrophic hormone secreting tumor
adenoma of either posterior or intermediate lobe; causes a syndrome of cortical excess (Cushing's syndrome).
References in periodicals archive ?
Adrenocorticotrophic hormone; adrenocortical steroids and their synthetic analogs; inhibitors of the synthesis and actions of adrenocortical hormones.
Other medical options for young children, particularly those with myoclonic seizures, include the use of high-dose steroids, especially adrenocorticotrophic hormone (ACTH).
Stress responses of animals are excited mainly by the activation of hypothalamic-pituitary-adrenal (HPA) axis and the adrenocorticotrophic nervous system (Ishii et al.
Relationship between plasma adrenocorticotrophic hormone and cortisol concentrations in chronic alcoholic patients with depression.
Ectopic adrenocorticotrophic (ACTH) syndrome and small cell carcinoma of the lung-assessment of clinical implications in patients on combination chemotherapy.
The reversibility of certain rheumatic and non-rheumatic conditions by the use of cortisone or of the pituitary adrenocorticotrophic hormone.
Despite high serum levels of cortisol, these patients often present with a relative adrenal insufficiency, defined as a blunted increase in cortisol levels after stimulation with adrenocorticotrophic hormone (ACTH) (4).
Growth hormone deficiency is reported to be the earliest manifestation followed by follicle-stimulating hormone/luteinizing hormone, thyroid stimulating hormone and adrenocorticotrophic hormone deficiencies (14).
Pancreatic endocrine neoplasms may express normally produced pancreatic hormones (insulin, glucagon, somatostatin, pancreatic polypeptide), hormones of ectopic origin (gastrin, vasoactive intestinal polypeptide, adrenocorticotrophic hormone), and bioamines (serotonin).
Animal studies have also shown that short adrenocorticotrophic hormone (ACTH) fragments relieve vertigo symptoms and accelerate their disappearance.
Within the anterior pituitary the CRF acts to induce proopiomelanocortin (POMC), which cleaves to form adrenocorticotrophic hormone (ACTH).
It then is transported to the anterior pituitary, where it binds to CRF receptors (CRF 1 and CRF2), thereby eliciting the release of adrenocorticotrophic hormone (ACTH).

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