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Related to adrenergic agonist: Adrenergic antagonist
adrenergic agonistA family of agents which have adrenaline-like effects, acting directly or indirectly on any of the five G-protein-coupled adrenergic receptors: apha1, alpha2, beta1, beta2, beta3.
Actions of adrenergic agonists
alpha1 receptors: Activate phospholipase C (via Gq), increasing protein kinase C activity.
alpha2: receptors Inhibit adenylate cyclase (via G1), decreasing protein kinase A activity.
beta receptors: Activate adenylate cyclase (via Gs), increasing protein kinase A activity.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Any of a group of therapeutic agents, e.g. epinephrine, that mimic or stimulate the sympathetic nervous system.
See also: agonist
Medical Dictionary, © 2009 Farlex and Partners
Drugs that produce an effect similar to that obtained by stimulation of the sympathetic nervous system. Some of these predominantly act on the adrenergic alpha-receptors (e.g. noradrenaline (norepinephrine)), while others act on the adrenergic beta-receptors (e.g. isoproterenol). Others have little direct effect on the adrenergic receptors but enhance the release of natural catecholamine from the sympathetic nerve terminals (e.g. amphetamine, phenylpropanolamine). Sympathomimetic drugs are used (1) in the treatment of open-angle glaucoma by decreasing aqueous humour secretion and increase the outflow through the trabecular meshwork thus reducing the intraocular pressure (e.g. adrenaline (epinephrine), apraclonidine, dipivefrine hydrochloride, brimonidine tartrate), (2) dilate the pupil without affecting accommodation (e.g. phenylephrine) and (3) constrict conjunctival blood vessels (e.g. naphazoline, tetrahydrozoline). Syn. adrenergic agonist; adrenergic stimulating agent. See alpha-adrenergic agonist; mydriatic.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
ad·re·ner·gic ag·o·nist(adrĕ-nĕrjik agŏ-nist)
An agent capable of combining with receptors to initiate actions of or like epinephrine.
See also: epinephrine
See also: epinephrine
Medical Dictionary for the Dental Professions © Farlex 2012