adrenal suppression

the most common cause of adrenal insufficiency, usually iatrogenic, as a result of long-term use of glucocorticoids, particularly critical in stress situations.

References in periodicals archive ?

Is adrenal suppression in asthmatic children reversible?

Asthma treatment in children: A guide to screening for and management of hypothalamic-pituitary-adrenal axis suppression

Corticosteroids are synthetic forms of cortisol.2 They are usually prescribed in a once a day regimen to match the normal circadian rhythm of steroid hormones and to avoid adrenal suppression.4 Despite being life-saving, steroids have many adverse effects.

Frequency of steroid induced hyperglycemia in patients with dermatological disorders

Unfortunately, corticosteroids can also cause side effects, one of which is adrenal suppression, seen in up to 1/3 of people tested.

Genetic variant discovery to help asthma sufferers

In a world first, the University of Liverpool researchers, led by Sir Munir Pirmohamed, conducted a genome-wide association study (GWAS) to pinpoint the genes responsible for increasing the risk of a person developing adrenal suppression.

New genetic find offers hope for asthma sufferers

They might have some value to check the grade of adrenal suppression they may cause.

Cortisol Deficiency: Frequent, Life-Impairing, and How to Give Patients Their Lives Back by Correcting It, Part 2

Trials on the use of ICSs in CF for the treatment of allergic bronchopulmonary aspergillosis did not systematically evaluate adverse events, although the total daily dose of ICSs was at the threshold of adrenal suppression in most studies [4].

Adrenal Insufficiency in Cystic Fibrosis: A Rare Phenomenon?

What many of these cases share is the inhibition of CYP3A4 which results in supraphysiologic levels of corticosteroids (inhaled, intranasal, intra-articular, or oral) leading to iatrogenic Cushing's syndrome with resultant adrenal suppression. There are also case reports of itraconazole-induced central adrenal insufficiency, but in all cases, it was thought to be due to a drug interaction with inhaled corticosteroids [13, 14].

Posaconazole-Induced Adrenal Insufficiency in a Case of Chronic Myelomonocytic Leukemia

Suppression of HPA axis is a well-known and tested effect of exogenous therapy with glucocorticoids (GCs) and GC therapy is the most common cause of adrenal suppression.

GLUCOCORTICOID THERAPY AND ADRENAL SUPPRESSION/TERAPIJA GLUKOKORTIKOIDIMA I ADRENALNA SUPRESIJA

The prescribing information says that mometasone furoate exerts less effect on the hypothalamic-pituitary-adrenal axis than other inhaled corticosteroids, and that adrenal suppression is unlikely to occur when used at recommended dosages.

Asthma inhaler linked to adrenocorticotropic suppression

Patients taking steroids have a significant risk of Adrenal suppression caused due to suppression of hypothalamic pituitary axis leading to adrenal insufficiency.

Experiences with Thalidomide for Erythema Nodosum Leprosum--a retrospective study

Seven studies with a primary end-point of adrenal suppression performed on 1303 patients were analyzed separately.

Comments on etomidate usage in the emergency department

Adrenal suppression levels of serum cortisol; taken at 0800 hrs following 3 weeks of treatment, less than 3 ug/dl (83nmol/l) was taken as cases of adrenal suppression.

FREQUENCY OF SERUM CORTISOL SUPPRESSION IN PATIENTS USING 0.05% CLOBETASOL PROPIONATE AS TOPICAL STEROID FOR MORE THAN 3 WEEKS