(13) as a second-line imaging examination in 48 out of 230 patients, referred with a variety of penoscrotal diseases, including a small number of benign intratesticular pathologies, namely four cases of acute epididymoorchitis, two cases of intratesticular cysts, one
adrenal rest tissue, three cases of torsion, four cases of trauma, four cases of hydrocele and two inguinal hernias.
Holmedal et al., "High frequency of adrenal myelolipomas and testicular
adrenal rest tumours in adult Norwegian patients with classical congenital adrenal hyperplasia because of 21-hydroxylase deficiency," Clinical Endocrinology, vol.
Furthermore, 21-deoxycortisol and 11oxC19 steroids showed the closest correlation with adrenal gland size and 11oxC19 steroids were detected at much higher concentrations in CAH patients with testicular
adrenal rest tumor (TART) than those without (11).
Patient has not had testicular ultrasound to evaluate for testicular
adrenal rest tumor (TART).
In adult males, the condition is mainly asymptomatic, but some men may present with
adrenal rest tumour and/or fertility problems.8
The nodule in the spermatic cord contained morphological features consistent with an
adrenal rest (Fig.
Recent studies suggested that development of testicular
adrenal rest tumors (TARTs), which cause an obstruction of the seminiferous tubules, may play a major role [1,2].
The child should also be monitored for Cushingoid features due to excessive steroid intake and for the development of
adrenal rest tumors in the testis, a well-known complication in male children and adults with classic CAH [6].
In patients with CAH, ectopic
adrenal rest tissue is frequently identified within the testicles.
The diagnosis of testicular
adrenal rest tumor had been confirmed by clinical, morphological, immunohistochemical, laboratory, and endocrinological evaluations, and the patient was referred to endocrinology clinic for future treatment.
If compliance is poor, excess androgen production, accelerated growth, secondary central precocious puberty and, in boys,
adrenal rest tumours can occur, as in the following case.
Testicular
adrenal rest tumor (TART) is a benign tumor which is seen in male patients who have congenital adrenal hyperplasia (CAH).
