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hemorrhage into the suprarenal glands or thrombosis of the suprarenal veins, followed by acute adrenal insufficiency, occurring in the Waterhouse-Friderichsen syndrome.
ad·re·nal ap·o·plexy (ă-drēnăl apō-pleks-ē)
Hemorrhage into the suprarenal glands or thrombosis of the suprarenal veins, followed by acute adrenal insufficiency.
adrenal apoplexy Acute catastrophic failure of the adrenal glands often resulting from massive bleeding into the glands with destruction of gland tissue. The condition is usually a response to severe bodily injury or systemic infections but may result from heart disease, acute alcoholic poisoning, anticoagulation treatment or coagulation disorders. In adrenal apoplexy the output of cortisol is very low, far lower than the shock situation requires, and the danger to the patient correspondingly high. In those who survive, long-term hormone replacement therapy is necessary.