ADOPT

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ADOPT

Cardiology
Accupril Decision On PharmacoTherapy. A clinical trial that was planned at Vanderbilt University in Tennessee, the purpose of which was to compare efficacy and safety of quinapril, enalapril, atenolol and verapamil in controlling blood pressure in patients with uncomplicated mild to moderate hypertension when used as single-agent therapy in a structured titration program.
 
Endocrinology
A Diabetes Outcome Progression Trial. A 4-year Phase-4 trial comparing early treatment of type-2 diabetics with rosiglitazone (Avandia), metformin or glyburide (a sulfonylurea in glucose control) for delay or prevention of diabetes complications—e.g., kidney disease, etc.

Conclusion
Lower failure rate at 5 years: 15% with rosiglitazone vs. 21% with metformin and 34% with glyburide; a highly significant risk reduction of 32% for rosiglitazone compared with metformin, and 63% compared with glyburide. Positive results notwithstanding, rosiglitazone has been pulled from various markets due to possible increased risk of heart attacks.

ADOPT

Endocrinology A 4-yr phase IV trial–A Diabetes Outcome Progression Trial–comparing early treatment of Pts with type 2 DM with Avandia®, metformin, or glyburide–a sulfonylurea in glucose control, delay or prevention of DM complications–eg, kidney disease, etc
References in periodicals archive ?
The dogs benefit through exposure to human contact and by learning behaviors that make them more readily adoptable and more attractive pets.
More than 70 percent of the cats last year were adoptable and about 80 percent of those were adopted out.
Consumers who download the Dogpile adoptable pet widget application will have easy access to information on pets available for adoption through Petfinder.
There will also be complimentary snacks and refreshments, and of course, plenty of adorable and adoptable dogs, cats, and rabbits.
Throughout the event they will be showcasing adoptable pets in their "Rescue Rocks The Runway" fashions, which will be available for purchase.
This is not a walk in the park,'' said Mei Lin Kroll, a 30-year-old West Los Angeles loan officer, who is the adopted daughter of Joe Kroll, executive director of North American Council on Adoptable Children.
Puppies and kittens are already being transferred between counties to alleviate a shortage of adoptable pets: San Francisco and Marin Counties need to bring pets in from other areas to be adopted locally.
For more information or to view more adoptable animals, go online to www.
SVACA's adoptable animals will be available for a $50 adoption fee which is 50% off the regular adoption fees.
Shelters that claim ``no adoptable animal is killed'' are private SPCAs that take in only selected, desirable animals and publish their 100 percent adoption rate.
Whether it is a cityscape or a beach motif, these habitats will not only entertain visitors, but also provide safe, comfortable and enriching environments for adoptable pets.
Critics, though, contend that in practice the program might be keeping adoptable pets from finding homes while subjecting them to health problems.