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ADOPT

Cardiology
Accupril Decision On PharmacoTherapy. A clinical trial that was planned at Vanderbilt University in Tennessee, the purpose of which was to compare efficacy and safety of quinapril, enalapril, atenolol and verapamil in controlling blood pressure in patients with uncomplicated mild to moderate hypertension when used as single-agent therapy in a structured titration program.
 
Endocrinology
A Diabetes Outcome Progression Trial. A 4-year Phase-4 trial comparing early treatment of type-2 diabetics with rosiglitazone (Avandia), metformin or glyburide (a sulfonylurea in glucose control) for delay or prevention of diabetes complications—e.g., kidney disease, etc.

Conclusion
Lower failure rate at 5 years: 15% with rosiglitazone vs. 21% with metformin and 34% with glyburide; a highly significant risk reduction of 32% for rosiglitazone compared with metformin, and 63% compared with glyburide. Positive results notwithstanding, rosiglitazone has been pulled from various markets due to possible increased risk of heart attacks.

ADOPT

Endocrinology A 4-yr phase IV trial–A Diabetes Outcome Progression Trial–comparing early treatment of Pts with type 2 DM with Avandia®, metformin, or glyburide–a sulfonylurea in glucose control, delay or prevention of DM complications–eg, kidney disease, etc
References in periodicals archive ?
The dogs benefit through exposure to human contact and by learning behaviors that make them more readily adoptable and more attractive pets.
More than 70 percent of the cats last year were adoptable and about 80 percent of those were adopted out.
There will also be complimentary snacks and refreshments, and of course, plenty of adorable and adoptable dogs, cats, and rabbits.
Throughout the event they will be showcasing adoptable pets in their "Rescue Rocks The Runway" fashions, which will be available for purchase.
For more information or to view more adoptable animals, go online to www.
SVACA's adoptable animals will be available for a $50 adoption fee which is 50% off the regular adoption fees.