adjuvanticity

adjuvanticity

/ad·ju·van·tic·i·ty/ (aj″dbobr-van-tis´ĭ-te) (ă-joo″van-tis´ĭ-te) the ability to modify the immune response.
References in periodicals archive ?
Objective: This proposal originates from recent results obtained in the course of the advanced erc project omvac , The scope of which is to exploit the unique adjuvanticity properties of bacterial outer membrane vesicles (omvs) for developing innovative vaccines against infectious diseases and cancer.
Background: The adjuvanticity potential of Lactobacillus casei was first suggested in an old survey.
104) CT and LT are multisubunit macromolecules that comprise an active A subunit, which confers the biologic activities of toxicity and adjuvanticity, and a GM1 ganglioside-binding B subunit that lacks toxicity.
the length, the number, and the composition of sugar side chains affecting the HLB value would give the overall conformation of each saponin molecule, and the amphipathic structure may define the fundamental adjuvanticity of saponins (Oda et al.
A role of IgM antibodies in monosodium urate crystal formation and associated adjuvanticity.
Adjuvanticity and protective immunity elicited by Leishmania donovani antigen encapsulated in positively charged liposomes.
Adjuvanticity of CTB or LTB is much improved when coupled to antigens.
Many of these systems hold promise for future vaccine strategies, but only a few have been tested in humans for safety and adjuvanticity.
Does adjuvanticity depend on the ability to recruit specific immune cells?
Intrinsic adjuvanticity and propensity to be manipulated potentially make OMVs an ideal vaccine platform, particularly indicated when antigen combinations (for pathogens with genetic variability) and strong potentiation of immunity (for the elderly and cancer) are needed.
However, subsequent studies indicated that the ADP-ribosyltransferase activity was not essential for the adjuvant function, and that separation of this toxic component in many instances did not hamper the adjuvanticity appreciably (52).
Adjuvanticity and protective immunity elicited by Bordetella pertussis antigens encapsulated in poly(DL-lactide-coglycolide) microspheres.