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Autocrine and paracrine factors released from human adipose tissue, in particular the visceral depots; including cytokines, acute phase reactants, growth factors, and other inflammatory mediators. Many are involved in the pathogenesis of hypertension, insulin resistance, and atherosclerosis.
Synonym(s): adipocytokines.
[adipo- + G. kineō to set in motion]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Although adipose tissue does not contribute much in glucose disposal, the production of free fatty acids and adipocytokines modulate insulin sensitivity in the peripheral tissues especially liver and skeletal muscles10.
Intrauterine growth restriction and adult disease: the role of adipocytokines. Eur J Endocrinol 2009;160:337-347.
Adipocytokines as new promising markers of colorectal tumors: adiponectin for colorectal adenoma, and resistin and visfatin for colorectal cancer.
Gestational diabetes mellitus causes changes in the concentrations of adipocyte fatty acid-binding protein and other adipocytokines in cord blood.
Adipocytes create cytokines and adipocytokines with basic administrative consequences for inflammation, insulin sensitivity, coagulation, vascular homeostasis, hunger, energy, and so on.
Adipocytokines and the expanding 'Asian Indian Phenotype'.
The adipose tissue not only serves as an energy storage but also acts as an endocrine tissue that releases various proteins called adipocytokines (1).
Hypoxia has been proposed to induce production of biologically active metabolites - adipocytokines which include C-reactive protein, plasminogen activator inhibitor-1, and proinflammatory mediators (tumor necrosis factor-[alpha], interleukin-6 (IL-6).
The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 diabetes mellitus.
Coffee also caused a cascade of other beneficial changes in the fatty liver and inflammatory adipocytokines related to a reduced diabetes risk.
The possible mechanism is that during adipogenesis, a feedback inhibition in its production may occur due to increase in the production of other adipocytokines like TNF-[+ or -] that decrease adipocyte expression and secretion of adiponectin (28).