Visceral adipose tissue-specific serpin (vaspin) is a newly discovered adipocytokine
secreted mainly by visceral adipose tissue that has insulin-sensitizing effects (5).
Libby, "Adiponectin: a key adipocytokine
in metabolic syndrome," Clinical Science, vol.
Adiponectin (also termed acrp 30, adipoQ, APM-1, GBP28) is an adipocytokine
that is generally and abundantly expressed in adipose tissue and directly sensitizes the cells to insulin.
Markers of endothelial injury and plasma adipocytokine
in antiretroviral-naive HIV patients.
Thus, the data obtained so far suggest that adiponectin is an important insulin-sensitizing adipocytokine
. Furthermore, it appears that various factors might increase or decrease insulin sensitivity at least partly by up- or down-regulating adiponectin.
A person's body weight, fat content and overall metabolic state are pertinent modifiers for puberty and fertility.1 Metabolic stress in terms of over nutrition and under nutrition is frequently linked to reproductive disorders.2 The connection between energy balance and reproduction are linked with the discovery of adipocytokine
however, our understanding of the neurobiological basis for this phenomenon is still incomplete.
It is a pleiotropic adipocytokine
which regulates the ingestion of foods, energy consumption, immunity, inflammation, hematopoiesis, cell differentiation, and proliferation [6, 7].
Wolzt, "The release of the adipocytokine
visfatin is regulated by glucose and insulin," Diabetologia, vol.
(leptin) together with TSH is involved in causing abnormalities in thyroid function tests via insulin-like growth factor 1 (IGF-1)11.
Nevertheless, the circulating levels of adiponectin, which is the most abundant adipocytokine
, are reduced in conditions such as obesity, type 2 diabetes, and coronary heart disease (CHD) [26-28].
Kauppi et al., "Predictive value of pretretment adipocytokine
levels for remission rates in early RA treated with DMARDS and infliximab," Basic & Clinical Pharmacology & Toxicology, vol.
Resistin, an adipocytokine
, was initially discovered in a research conducted on obese rodents to probe the missing link between obesity, diabetes mellitus and insulin resistance.