adipocytokine

Adipokine

A generic term for cytokines and other modulating proteins which are secreted by adipocytes. Some—e.g., IL-6—are pro-inflammatory,  whilst others—e.g., adiponectin—have anti-inflammatory or insulin-sensitising properties. Adipokine dysregulation appears to play a central role in adiposity, metabolic syndrome, and the co-morbidities of obesity including cardiovascular disease.

adipocytokine

, adipokine (ad″ĭ-pō-sīt′ŏ-kīn″) (ad′ĭ-pŏ-kīn″) [ adipo- + cytokine]
A molecule secreted by fat cells that affects the physiology of cells in other parts of the body. Some of these molecules influence appetite, the storage of fat in the body, and systemic inflammation.
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References in periodicals archive ?
8 Adiponectin is the only adipocytokine that has insulin-sensitising property.
Resistin is an adipocytokine whose effects on glucose metabolism are antagonistic to those of insulin8.
Noting that Artemis is exploring the weight management potential of berries or other sources of anthocyanins such as purple corn, he adds, "Anthocyanins influence adipocytokine expression and show exciting anti-obesity potential in animal trials.
Levels of the adipocytokine leptin--known to be related to insulin resistance--increased stepwise from the normal to the overweight to the metabolic syndrome subjects.
Adiponectin (Acrp30), an adipocytokine, is important in many therapeutic arenas, including type 2 diabetes, obesity, atherosclerosis, and rheumatoid arthritis.
Influence of epicardial adipose tissue and adipocytokine levels on cardiac abnormalities in visceral obesity.
Adiponectin (also termed acrp 30, adipoQ, APM-1, GBP28) is an adipocytokine that is generally and abundantly expressed in adipose tissue and directly sensitizes the cells to insulin.
Conclusion: Visfatin is a potential antilipidemic adipocytokine that probably modulates insulin sensitivity and decreases atherogenic lipids (triglycerides, cholesterol, LDL and VLDL) with concomitant increase in HDL in obesity and diabetes mellitus.
Markers of endothelial injury and plasma adipocytokine in antiretroviral-naive HIV patients.
Lipoatrophic diabetes in an elderly woman: clinical course and serum adipocytokine concentrations.
Regulation of adipocytokine secretion and adipocyte hypertrophy by polymethoxyflavonoids nobiletin and tangeretin.