adipocyte


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Related to adipocyte: reticular fiber

adipocyte

 [ad´ĭ-po-sīt″]
fat cell.

fat cell

a connective tissue cell distended with one or more fat globules, the cytoplasm usually being compressed into a thin envelope, with the nucleus at one point in the periphery.

adipocyte

(ăd′ə-pō-sīt′)
n.

Adipocyte

A generic term for any fat-storing cell, either:
(1) White (yellow, or adult) fat cells, which are far more common. These are unilocular—i.e., their cytoplasm contains a single humongous lipid-rich vacuole containing triglycerides and cholesteryl ester that flattens the remaining cytoplasm and nucleus to the outer edge. White fat cells—all 30 billion of them—secrete adiponectin, leptin and resistin, and weigh 13 kg/2 stone/30 lbs. White adipocytes divide once they grow beyond 4 times their usual size.
(2) Brown (baby) fat cells are multilocular and polygonal. In contrast to white fat cells, brown fat cells are rich in mitochondria and generate heat.

fat cell

(fat sel)
A connective tissue cell distended with one or more fat globules, the cytoplasm usually being compressed into a thin envelope, with the nucleus at one point in the periphery.
Synonym(s): adipocyte, adipose cell.

adipocyte

A fat cell. A cell that synthesizes and stores neutral fats (triacylglycerols or TRIGLYCERIDES). Human fat is a liquid at body temperature, so adipocytes are normally filled with oil. Adipocytes develop from adipoblasts, which derive from fibroblasts.
References in periodicals archive ?
Immunohistochemical (perilipin) and histologic (H and E) examination of samples showed better-maintained integrity of adipocytes in fat grafts treated with topical curcumin, and less cellular infiltration, hemorrhage, cyst/vacuole formation, and more vascularization in both the early and the late period.
Perilipin A, a membrane protein located on adipocyte lipid vacuoles, as well as CD31 and von Willebrand factor (vWF), both endothelial proteins, were evaluated as markers of cell specificity on day 0, 7, and 14 by immunofluorescence staining.
Knockout of IRX3 expression in mice caused an increase in uncoupling protein 1 (UCP1) gene expression in white adipose cells which is an important factor of browning white adipocytes.[2] However, contradictory results were found in this area.
In accordance with previous findings, knockdown of XBP1 (Figure 3(b)) significantly impairs the differentiation of preadipocytes as demonstrated by oil accumulation (Figure 3(a)) as well as adipocyte differentiation marker aP2 transcription (Figure 3(d)).
Spiegelman, "mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer," Genes & Development, vol.
However, we found no difference in adipocyte DIO2 gene expression between obese diabetic and nondiabetic patients in either SAT (3.11 [+ or -] 1.00 versus 3.01 [+ or -] 0.38, p = 0.465) or VAT (2.44 [+ or -] 0.33 versus 2.01 [+ or -] 0.81, p = 0.455) (Figure 1(d)).
Immunohistochemical staining of the signet ring cells demonstrated these cells to be negative for AE1/AE3, CD138, or Kreyberg staining while being positive for S-100 staining (Figures 1(e) and 1(f)); the immunoprofile was most consistent with atrophic adipocytes rather than signet ring cell carcinoma.
Hinokitiol Inhibits the Adipocyte Differentiation of MSCs through the AMPK Pathway.
In adipocytes, whether TLR9/KLF4 plays an anti-inflammatory role in FFA-induced inflammatory response has not been reported.
In AT development, formation of new adipocytes via differentiation of progenitor cells is intimately coupled to the ensuing expansion of adipocytes (hypertrophy) via lipid accumulation; the enzymes and regulatory proteins responsible for lipid droplet (LD) formation are also markers of differentiation.
Hoon et al., "SGBS cells as a model of human adipocyte browning: a comprehensive comparative study with primary human white subcutaneous adipocytes," Scientific Reports, vol.