Phosphorylation of the Drosophila adherens junction
protein Armadillo: roles for wingless signal and zeste-white 3 kinase.
Under these conditions, only the adherens junctions
remain intact, and the epithelium with the adherens junction
intact continues to impede the entrance of high molecular weight dextrans.
beta]- or [gamma]-catenin binds [alpha]-catenin to stabilize the adherens junction
anchorage to the actin cytoskeleton.
(AJs) are defined by the presence of cadherins (Takeichi, 1991), and are the major junctional type required for cell-cell adhesion across the Metazoa (Oda et al.
Mitogen-activated protein kinases, adherens junction
dynamics, and spermatogenesis: A review of recent data," Developmental Biology 286(1): 1-15.
Interactions among IQGAP1, Cdc42, and the cadherin/catenin protein complex regulate Sertoli--germ cell adherens junction
dynamics in the testis," Journal of Cellular Physiology 202(1): 49-66.
QUESTION: Is the actin-mediated adherens junction
disrupted by the presence of desmosomal cadherins that shouldn't be able to link up?
Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions
in the seminiferous epithelium of the rat testis," Journal of Andrology 25(2): 200-215.
Sertoli-germ cell adherens junction
dynamics in the testis are regulated by RhoB GTPase via the ROCK/LIMK signaling pathway," Biology of Reproduction 68(6): 2189-2206.
and TJs play an important role for protecting the intestinal barrier.
beta]-catenin is the principal component of adherens junctions
at cell-cell contact and is anchored to the cytoskeleton to support cellular architecture and organization of the cytoskeleton.
Using the Drosophila developing leg as a model system to study apoptosis-dependent epithelium folding, we have recently shown that apoptotic cells produce a pulling force through the unexpected maintenance of their adherens junctions
that serves as an anchor to an apico-basal Myosin II cable.