adenylyl cyclase


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Related to adenylyl cyclase: Phospholipase C, Protein kinase A

a·den·y·lyl cy·clase

former name for adenylate cyclase.
References in periodicals archive ?
The relation of increased adenylyl cyclase activation, antidepressant treatment response, low extraversion properties, and mental stress-related cardiovascular disorders reveals the importance of those polymorphisms.
Karpen, "Cyclic NucleotideGated Channels Colocalize with Adenylyl Cyclase in Regions of Restricted Camp Diffusion," J.
The medicinal activities of forskolin are due to its ability to activate the enzyme adenylyl cyclase and therefore to increase the levels of cyclic AMP (cAMP) in the cells.
The G-proteins begin a cascade that ultimately leads to activation of the enzyme adenylyl cyclase that produces cAMP.
The results of other studies measuring ethanol consumption in animals in which genes such as those encoding proteins called adiponectin receptor 2, agouti-related protein, neurokinin-1 receptor, PSD-95, and adenylyl cyclase type 5 had been knocked out have yet to be confirmed in independent studies.
DRD1 and DRD5 activate adenylyl cyclase and increase cAMP production.
These cells may also participate in inflammatory responses, as they produce the cytokine IL-6 in response to [beta]-adrenergic receptor ([BETA]AR) stimulation of adenylyl cyclase (AC).
In contrast to alpha-1 receptors, the effects of binding at alpha-2 receptors are mediated by inhibition of adenylyl cyclase and a fall in the levels of intracellular cAMP (25).
The scientists reported that the Rac-dependent forgetting mechanism in flies did not affect mechanisms involved in the formation of new memories, specifically a pathway associated with the gene Rutabaga that is mediated by the enzyme adenylyl cyclase.
Recent studies have indicated that organophosphorus pesticides (OPs) may disrupt metabolism by altering the expression or function of adenylyl cyclase (AC; the enzyme that catalyzes the formation of cAMP from ATP) or G-protein-coupled receptors and G-proteins involved in the AC signaling cascade.
Genetic variation of the adenylyl cyclase 3 (AC3) locus and its influence on type 2 diabetes and obesity susceptibility in Swedish men.
Glucagon binds to its receptors in the plasma membranes of adipocytes, activating (via a Gs protein) adenylyl cyclase, during fasting state glucagon increases blood glucose via hepatic glycogenolysis or gluconeogenesis and it stimulates adipose tissue to release fatty acids through lipolysis.