adenylyl

a·den·y·lyl

(a-den'i-lil),
The radical of adenylic acid minus an OH from the phosphoryl group; often shortened to adenyl in compound names, such as adenylosuccinic acid.
References in periodicals archive ?
Estrogens acting via GPR30 are capable of stimulating adenylyl cyclase activity, which in turn leads to PKA-mediated suppression of EGFR-ERK (Filardo et al.
The scientists reported that the Rac-dependent forgetting mechanism in flies did not affect mechanisms involved in the formation of new memories, specifically a pathway associated with the gene Rutabaga that is mediated by the enzyme adenylyl cyclase.
Glucagon binds to its receptors in the plasma membranes of adipocytes, activating (via a Gs protein) adenylyl cyclase, during fasting state glucagon increases blood glucose via hepatic glycogenolysis or gluconeogenesis and it stimulates adipose tissue to release fatty acids through lipolysis.
For example, the [alpha]S-subunit binds to and activates an enzyme protein called adenylyl cyclase.
Stimulation of the Beta 1 adrenergic receptor by catecholamines activates the heterotrimeric G-protein, which, in turn activates the enzyme adenylyl cyclase, and promotes cyclic AMP production.
FSC is an adenylyl cyclase activator like Forskolin, but is less expensive.
Platelet adenylyl cyclase activity as a trait marker of alcohol dependence.
Storm, "The diurnal oscillation of MAP (mitogen-activated protein) kinase and adenylyl cyclase activities in the hippocampus depends on the suprachiasmatic nucleus," Journal of Neuroscience, vol.
The activity of it is mediated by G proteins which activate adenylyl cyclase.[sup][29] The PRLR is a cytokine receptor, and second messenger cascades include the JAK-STAT pathway, JAK-RUSH pathway, Ras-Raf-MAPK, and PI3K/AKT/mTOR pathway.[sup][30]
This binding with TSH receptors activates two postreceptor cascades: one involves adenylyl cyclase, leading to an increase of intracellular cyclic AMP and protein kinase A phosphorylation and also to an activation of cytosolic and nuclear target proteins; the other is inositol-dependent and involves the phospholipase C-dependent inositol phosphate [Ca.sup.2+]/diacylglycerol pathway, resulting in a boost of hydrogen peroxide ([H.sub.2][O.sub.2]) generation.