adenylate kinase


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a·den·y·late ki·nase

adenylic acid kinase; a phosphotransferase that catalyzes the reversible phosphorylation of a molecule of ADP by MgADP, yielding MgATP and AMP.

Adenylate Kinase

A phosphotransferase that catalyses the reaction ATP + AMP = 2 ADP in red cells and muscle and plays a critical role in intracellular energy homeostasis.
Human genes encoding adenylate kinases AK1, AK2, AK3, AK5, AK3L1, CMPK1, CMPK2.

a·den·y·late ki·nase

(ă-den'i-lāt kī'nās)
Adenylic acid kinase; a phosphotransferase that catalyzes the reversible phosphorylation of a molecule of ADP by MgADP, yielding MgATP and AMP.

adenylate kinase

an ENZYME that catalyses the transfer of a PHOSPHATE group from adenosine triphosphate (ATP) to adenosine monophosphate (AMP) to produce two molecules of adenosine diphosphate (ADP). The enzyme can also generate ATP (and AMP) from 2ADP by the reverse reaction:

References in periodicals archive ?
Bae E, Phillips GNJr (2006) Roles of static and dynamic domains in stability and catalysis of adenylate kinase. Proc.
Willemoes M, Kilstrup M (2005) Nucleoside triphosphate synthesis catalysed by adenylate kinase is ADP dependent.
Adenylate kinase locus 1 polymorphism and feto-placental development.
Genetically determined variation of adenylate kinase in man.
Praskevicius, "The effect of adenylate kinase activity on the rate and efficiency of energy transport from mitochondria to hexokinase," Biochemistry International, vol.
Gellerich, "Experimental evidence for dynamic compartmentation of ADP at the mitochondrial periphery: coupling of mitochondrial adenylate kinase and mitochondrial hexokinase with oxidative phosphorylation under conditions mimicking the intracellular colloid osmotic pressure," Molecular and Cellular Biochemistry, vol.
Terzic, "Reversal of the ATP-liganded state of ATP-sensitive [K.sup.+] channels by adenylate kinase activity," Journal of Biological Chemistry, vol.
Evidence for competition by creatine kinase MM, adenylate kinase, malate and alcohol dehydrogenase.
The error per g/L Hemolink differs significantly from the reported effect of hemolysis on similar assays because of the presence of intracellular contaminants from erythrocytes (e.g., LDH, AST, K, and adenylate kinase) [7].