adenyl cyclase


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Related to adenyl cyclase: Adenylyl cyclase

ad·e·nyl cy·clase

(ad'e-nil sī'klās),
An enzyme that converts adenosine monophosphate to 3',5'-cyclic adenosine monophosphate, an intracellular second messenger of neural and hormonal activation.

adenyl cyclase

the enzyme that catalyses the formation of cyclic AMP (cAMP) from ATP by the removal of pyrophosphate.

ad·e·nyl cy·clase

(ad'e-nil sī'klās)
An enzyme that converts adenosine monophosphate to 3',5'-cyclic adenosine monophosphate, an intracellular second messenger of neural and hormonal activation.
References in periodicals archive ?
Bromocriptine is an ergot alkaloid derivative, structurally related to dopamine (1) Bromocriptine is a dopamine receptor agonist that inhibits prolactin secretion (2, 3, 4, 5) through the inhibition of adenyl cyclase activity (1) and is commonly used in the treatment of hyperprolactinemia, Parkinsonism and acromegaly (6,7).
It is known that all these receptors (alpha-2) couple to the inhibitory heterotrimeric GTP-binding protein (Gi) and inhibit adenyl cyclase (22).
The pharmacologic effects of a beta 2-adrenoceptor agonist drugs stimulate adenyl cyclase to cyclic 3'5' adenosine monophosphate (cyclic AMP).
Epinephrine, a primary messenger acts by activating the adenyl cyclase system which catalyzes the synthesis of cyclic AMP from ATP.
The mutation leads to a loss of guanosine triphosphatase activity and thus to adenyl cyclase overactivity and subsequent overproduction of cyclic adenosine monophosphate (cAMP).
In particular, tannic acid supplementation decreased both basal and isoproterenol-stimulated lipolysis significantly whereas cyclic AMP production as well as adenyl cyclase activity increased significantly.