adenyl


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ad·e·nyl

(ad'e-nil),
The radical or ion of adenine; often used for adenylyl, as in adenylosuccinic acid.

adenyl

/ad·e·nyl/ (ad´ĕ-nil)
1. the radical of adenine.
2. sometimes (incorrectly) used for adenylyl.

ad·e·nyl

(ad'ĕ-nil)
The radical or ion of adenine.

adenyl

(ad′ĕ-nil) [ aden- + -yl]
The radical C5H4N5; present in adenine.

adenyl cyclase

An enzyme that catalyzes the production of cyclic AMP (adenosine 3′,5′-cyclic monophosphate) from ATP (adenosine triphosphate). It is present on most cell surfaces.
References in periodicals archive ?
It is known that all these receptors (alpha-2) couple to the inhibitory heterotrimeric GTP-binding protein (Gi) and inhibit adenyl cyclase (22).
In vitro studies show that opioids inhibit activation of adenyl cyclase (6) and also stimulate the formation of cGMP (7).
The pharmacologic effects of a beta 2-adrenoceptor agonist drugs stimulate adenyl cyclase to cyclic 3'5' adenosine monophosphate (cyclic AMP).
Cholera--The cholera enterotoxin produced by Vibrio cholerae stimulates adenyl cyclase, an intestinal enzyme that causes secretion of large volumes of watery fluid (as much as one L/hour).
Numerous enzymes, such as adenyl cyclase and protein kinase A involved in energy regulation, are upregulated by DHA.
Somatostatin receptors, an expanding gene family: cloning and functional characterisation of human SSTR3, a protein coupled to adenyl cyclase.
Epinephrine, a primary messenger acts by activating the adenyl cyclase system which catalyzes the synthesis of cyclic AMP from ATP.
Epinephrine activates the enzyme adenyl cyclase, which subsequently activates the phosphorylase enzyme system which, ultimately, converts glucose to glucose-6-phosphate (G6P).
ADP-induced platelet activation relies on the G protein response and the eicosanoid synthesis pathway to suppress adenyl cyclase activity and induce calcium mobilization to the platelet cytosol.
The mutation leads to a loss of guanosine triphosphatase activity and thus to adenyl cyclase overactivity and subsequent overproduction of cyclic adenosine monophosphate (cAMP).

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