carcinoma carcinoma of colon presenting as hypercalcemia.
36,85-88) Gastroesophageal adenocarcinoma has rare morphologic phenotypes that include adenosquamous
, papillary, and neuroendocrine carcinomas, (74) but data regarding HER2 expression in such morphologic variants are limited.
Other exocrine cancers include adenosquamous
carcinomas, signet ring cell carcinomas, hepatoid carcinomas, colloid carcinomas, undifferentiated carcinomas and undifferentiated carcinomas with osteoclast like giant cells.
and large-cell neuroendocrine carcinoma of the gallbladder.
5) In addition, NSCLC is often heterogeneous and can exist in an adenosquamous
subtype; one subtype may predominate in limited biopsy samples and provide misleading information in subtyping or treatment decisions.
TABLE 1 WHO CLASSIFICATION OF METAPLASTIC CARCINOMAS Purely epithelial Squamous -Large cell keratinizing -Spindle cell -Acantholytic Adenocarcinoma with spindle cell proliferation Adenosquamous
, including mucoepidermoid Mixed epithelial and mesenchymal -Carcinoma with chondroid metaplasia -Carcinoma with osseous metaplasia -Carcinosarcoma
One caveat is that some of the adenosquamous
carcinomas of the pancreas can be positive for BCL10.
16%) of adenosquamous
carcinoma was noted in 60 yr old multiparous women.
71,72) Rarely, this may undergo malignant transformation and give rise to metaplastic carcinoma--usually low-grade adenosquamous
The differential diagnosis of BSCC include adenoid cystic carcinoma, adenosquamous
carcinoma, spindle cell squamous carcinoma, mucoepidermoid carcinoma, adenoid squamous carcinoma, small cell neuroendocrine carcinoma, and basosquamous cell carcinoma.
The differential diagnosis included radial scar (RS), low-grade adenosquamous
carcinoma (LGASC), or benign entrapped glands at the edge of a sclerosing papillary lesion.
The two cases of uterine adenosquamous
carcinoma had infiltrated more than half of the myometrium (FIGO stage I B).