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A gene on chromosome 1q24 that encodes an enzyme belonging to the family of Na+/K+ and H+/K+ ATPases beta-chain proteins and the subfamily of Na+/K+ -ATPases, the latter of which are responsible for establishing and maintaining electrochemical gradients of Na and K ions across the plasma membrane; they are required for osmoregulation in sodium-coupled transport of various organic and inorganic molecules, and for electrical excitability of nerve and muscle. The ATP1B1 protein is the non-catalytic component of an active ATPase.
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"The smallest of the URF's is URFA6L, a 207-nucleotide (nt) reading frame overlapping out of phase the [NH.sub.2]-terminal portion of the adenosinetriphosphatase (ATPase) subunit 6 gene; it has been identified as the animal equivalent of the recently discovered yeast H+-ATPase subunit 8 gene" [2].
Rong, "Effects of Panax notoginseng saponins on myocardial adenosinetriphosphatase," Acta Pharmacologica Sinica, vol.
(1946) Adenosinetriphosphatase properties of myosin.
(1955) Adenosinetriphosphatase of Mytilus spermatozoa.
(1965) Dynein: a protein with adenosinetriphosphatase activity from cilia.
1993, "Inhibitory effects of modified bafilomycins and conacanamycins on P- and V- type adenosinetriphosphatases," Biochemistry, 32, pp.