adenosine kinase

a·den·o·sine ki·nase

[MIM*102750]
an enzyme catalyzing the transfer of a phosphate group from MgATP to adenosine, forming MgADP and AMP, an important step in nucleoside salvage and regulation.

adenosine kinase

an enzyme in the liver and kidney that catalyzes the transfer of a phosphate group from adenosine triphosphate to produce adenosine diphosphate.
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Masino and her colleagues found that mice with normal levels of adenosine A1 receptor (ALP,) and a transgenic overexpression of adenosine kinase, an intracellular enzyme that negatively influences extracellular levels of adenosine, had a "near complete" reduction in the number and duration of spontaneous seizures.
marketed (FDA approved) antivirals, including ribavirin (for RSV, respiratory syncytal virus) and related compounds (5 cpds); formycin analogs and polyoxometalates and dendrimers and 5 non carbocyclic adenosine analogues (totaling 11 new cpds); new apoptosis inhibitors and new cyclin-dependent kinase inhibitors (6 cpds) as well as adenosine kinase inhibitors (3 cpds); plus miscellaneous phospolipase, attachment / penetration and bunga virus inhibitors, plus cyclohexamide and a coumadin analog (totaling 7 cpds).

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