In the literature, various terminologies have been used for these exceptional lesions, including solitary peripheral ciliated glandular papillomas, peripheral pulmonary papillary/glandular neoplasms with ciliated cells, and mucinous adenomatous hyperplasia
. (20,23-26) The relationship between these lesions and CMPTs is intriguing and remains to be determined.
Nodular goitre is the most common benign lesion consisting of 41 cases, out of which 19 cases were showing adenomatous hyperplasia
changes; 34 cases were colloid nodule; 6 cases were positive for malignancy showing PCT.
We hypothesized that Hyal and HAS expressions also change in bronchial metaplasia and dysplasia, and in atypical adenomatous hyperplasia
, which are thought to be stages in the development of squamous cell lung carcinoma (25,26) and adenocarcinoma, respectively.
One study17 upon analysis of histopathology reports of Pipelle biopsy revealed secretory endometrium in 38.88% cases, proliferative endometrium in 34.92%, atrophic endometrium in 4.76%, adenomatous hyperplasia
and carcinoma endometrium was in 5.55% cases.
with increased ACTH production can occur independently or in association with similar changes in the native adrenals.[sup.1] The development of a neoplasm in an ectopic adrenal deposit is uncommon, yet phaeochromocytoma and Leydig cell tumours have been reported.[sup.10] Primary neoplastic tissue in the spermatic cord is also rare, but paragangliomas have been described.[sup.11]
In the revised edition of this classification dating 2001, the atypical adenomatous hyperplasia
or AAH was also mentioned as a separate entity, developing into adenocarcinoma of the lung .
This latter type of carcinoma likely arises from prostatic epithelium, often in association with AAH (Atypical Adenomatous Hyperplasia
), whereas the NTZ-PAC arises from PIN.
Other pathologies included multinodular goiter, adenomatous hyperplasia
, and hemorrhagic cysts.
Other possible--but as of now not well defined--features of concern are atypical adenomatous hyperplasia
, post-atrophic hyperplasia, and proliferative inflammatory atrophy.
(10,11) Standardization of pathologic descriptions (12) and the confirmation that adenomatous hyperplasia
is a precursor of endometrial carcinoma (13) have stimulated the American Cancer Society's interest in endometrial sampling as a potential screening tool in asymptomatic women.
Precursors of corpus cancer-4, adenomatous hyperplasia
as stage 0 carcinoma of endometrium.
In the 1999 (2) and 2004 (3) WHO classifications, atypical adenomatous hyperplasia
was recognized as a preinvasive lesion for lung adenocarcinoma.