Some of these polyps have been called mixed hyperplastic adenomatous
polyps / serrated adenomas by Longacre and Fenoglio-Preiser.
Invasive colonoscopy detected adenomatous
lesions not seen on virtual colonoscopy in 19 of 160 patients.
Data was also presented at the meeting on celecoxib, a COX-2 inhibitor, currently being investigated to determine its potential to decrease the occurrence of new adenomatous
polyps (non-cancerous polyps occurring in the colon that can turn malignant).
For many average-risk patients, which includes those without previous adenomatous
polyps or a family history of colorectal cancer, performing colonoscopy only once or twice in a lifetime may be more attractive than more frequent screening using other modalities.
In a parallel study, the group located the gene for familial adenomatous
polyposis (FAP) on the same chromosome.
HONOLULU -- Video capsule endoscopy doesn't cut the mustard for evaluation of small bowel polyps in patients with familial adenomatous
Clinical results from familial adenomatous
polyposis (FAP) patients treated with Aptosyn(TM) (exisulind) for up to 18 months were presented today at the annual meeting of the American Gastroenterological Association (AGA) by Carol Burke, M.
The abstract also describes the current marker panel's modest ability to detect adenomatous
polyps as well, despite not having been developed or optimized for detection of pre-cancerous targets.
Almost 100% of patients with familial adenomatous
polyposis have developed duodenal adenomatosis by 70-75 years of age, reported Dr.
Gary Gordon of Searle will present the company's compelling findings on COX-2's implication in familial adenomatous
Recently, additional data have shown in a mouse model that mimics the clinical and genetic condition of Familial Adenomatous
Polyposis (FAP), that low oral doses of PX-12 produce marked decrease in the size and number of colon tumors.
SAN FRANCISCO -- Familial adenomatous
polyposis, although relatively rare, is a major concern for individuals and families affected by the condition, Dr.