adenoid cystic carcinoma


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carcinoma

 [kahr″sĭ-no´mah] (pl. carcinomas, carcino´mata)
a malignant new growth made up of epithelial cells tending to infiltrate surrounding tissues and to give rise to metastases. A form of cancer, carcinoma makes up the majority of the cases of malignancy of the breast, uterus, intestinal tract, skin, and tongue.
adenocystic carcinoma (adenoid cystic carcinoma) carcinoma marked by cylinders or bands of hyaline or mucinous stroma separated or surrounded by nests or cords of small epithelial cells, occurring in the mammary and salivary glands, and mucous glands of the respiratory tract. Called also cylindroma.
alveolar carcinoma bronchioloalveolar carcinoma.
basal cell carcinoma the most common form of skin cancer, consisting of an epithelial tumor of the skin originating from neoplastic differentiation of basal cells, rarely metastatic but locally invasive and aggressive. It usually occurs as small pearly nodules or plaques on the face of an older adult, particularly on a sun-exposed area of someone with fair skin. It has been divided into numerous subtypes on the basis of clinical and histological characteristics.
basosquamous carcinoma carcinoma that histologically exhibits both basal and squamous elements.
bronchioalveolar carcinoma (bronchiolar carcinoma) (bronchioloalveolar carcinoma) (bronchoalveolar carcinoma) a variant type of adenocarcinoma of the lung, with columnar to cuboidal epithelial cells lining the alveolar septa and projecting into alveolar spaces in branching papillary formations. Called also alveolar carcinoma or adenocarcinoma and bronchiolar, bronchioloalveolar, or bronchoalveolar adenocarcinoma.
bronchogenic carcinoma any of a large group of carcinomas of the lung, so called because they arise from the epithelium of the bronchial tree. Four primary subtypes are distinguished: adenocarcinoma of the lung, large cell carcinoma, small cell carcinoma, and squamous cell carcinoma.
cholangiocellular carcinoma a rare type of hepatocellular carcinoma arising from the cholangioles, consisting of two layers of cells surrounding a minute lumen. Called also bile duct carcinoma and cholangiocarcinoma.
chorionic carcinoma choriocarcinoma.
colloid carcinoma mucinous carcinoma.
cylindrical cell carcinoma carcinoma in which the cells are cylindrical or nearly so.
embryonal carcinoma a highly malignant germ cell tumor that is a primitive form of carcinoma, probably of primitive embryonal cell derivation; it usually arises in a gonad and may be found either in pure form or as part of a mixed germ cell tumor.
epidermoid carcinoma squamous cell carcinoma.
giant cell carcinoma a poorly differentiated, highly malignant, epithelial neoplasm containing many large multinucleated tumor cells, such as occurs in the lungs.
hepatocellular carcinoma primary carcinoma of the liver cells with hepatomegaly, jaundice, hemoperitoneum, and other symptoms of the presence of an abdominal mass. It is rare in North America and Western Europe but is one of the most common malignancies in parts of sub-Saharan Africa, Southeast Asia, East Asia, and elsewhere. A strong association seems to exist with chronic hepatitis B virus infection.
Hürthle cell carcinoma a malignant Hürthle cell tumor.
carcinoma in si´tu a neoplasm whose tumor cells are confined to the epithelium of origin, without invasion of the basement membrane; the likelihood of subsequent invasive growth is presumed to be high.
large cell carcinoma a type of bronchogenic carcinoma of undifferentiated (anaplastic) cells of large size, a variety of squamous cell carcinoma that has undergone further dedifferentiation.
medullary carcinoma that composed mainly of epithelial elements with little or no stroma.
mucinous carcinoma an adenocarcinoma that produces significant amounts of mucin.
nasopharyngeal carcinoma a malignant tumor arising in the epithelial lining of the nasopharynx, occurring at high frequency in people of Chinese descent. The epstein-barr virus has been implicated as a causative agent.
non–small cell carcinoma a general term comprising all lung carcinomas except small cell carcinoma, and including adenocarcinoma of the lung, large cell carcinoma, and squamous cell carcinoma.
oat cell carcinoma a form of small cell carcinoma in which the cells are round or elongated and slightly larger than lymphocytes; they have scanty cytoplasm and clump poorly.
papillary carcinoma carcinoma in which there are papillary growths that are irregular in nature arising from otherwise normal tissue; it can occur in the thyroid gland, the breast, or the bladder. Called also papillocarcinoma.
renal cell carcinoma carcinoma of the renal parenchyma, composed of tubular cells in varying arrangements; called also clear cell carcinoma.
scirrhous carcinoma carcinoma with a hard structure owing to the formation of dense connective tissue in the stroma. Called also fibrocarcinoma.
carcinoma sim´plex an undifferentiated carcinoma.
small cell carcinoma a common, highly malignant form of bronchogenic carcinoma in the wall of a major bronchus, occurring mainly in middle-aged individuals with a history of tobacco smoking; it is radiosensitive and has small oval undifferentiated cells. Metastasis to the hilum and to mediastinal lymph nodes is common.
spindle cell carcinoma squamous cell carcinoma marked by development of rapidly proliferating spindle cells.
squamous cell carcinoma
1. carcinoma developed from squamous epithelium, having cuboid cells and characterized by keratinization. Initially local and superficial, the lesion may later invade and metastasize.
2. the form occurring in the skin, usually originating in sun-damaged areas or preexisting lesions.
3. in the lung, one of the most common types of bronchogenic carcinoma, generally forming polypoid or sessile masses that obstruct the airways of the bronchi. It usually occurs in middle-aged individuals with a history of smoking. There is frequent invasion of blood and lymphatic vessels with metastasis to regional lymph nodes and other sites. Called also epidermoid carcinoma.
transitional cell carcinoma a malignant tumor arising from a transitional type of stratified epithelium, usually affecting the urinary bladder.
verrucous carcinoma
1. a variety of squamous cell carcinoma that has a predilection for the buccal mucosa but also affects other oral soft tissue and the larynx. It is slow-growing and somewhat invasive.
2. Buschke-Löwenstein tumor, so called because it is histologically similar to the oral lesion.

ad·e·noid cys·tic car·ci·no·ma

a histologic type of carcinoma characterized by large epithelial masses containing round, glandlike spaces or cysts that frequently contain mucus or collagen and are bordered by several layers of epithelial cells without intervening stroma, forming a cribriform pattern like a slice of Swiss cheese; perineural invasion and hematogenous metastasis are common; occurs most commonly in salivary glands and skin.

adenoid cystic carcinoma

Cylindroma Surgical pathology An uncommon carcinoma characterized by a cribriform or sieve-like pattern when viewed by low-power LM Sites sighted Salivary glands, as well as breast, cervix, lung and in the head & neck; in the salivary glands, ACC is indolent, but malignant with a tendency to recur and invade perineurial spaces. See Salivary gland tumor.

ad·e·noid cys·tic car·ci·no·ma

(ad'ĕ-noyd sis'tik kahr'si-nō'mă)
A histologic type of carcinoma characterized by round, glandlike spaces or cysts bordered by layers of epithelial cells without intervening stroma, forming a pattern like a slice of Swiss cheese; perineural invasion and hematogenous metastasis are common; occurs most commonly in salivary glands.
Synonym(s): cylindromatous carcinoma.

ad·e·noid cys·tic car·ci·no·ma

(ad'ĕ-noyd sis'tik kahr'si-nō'mă)
Histologic type of carcinoma characterized by large epithelial masses containing round, glandlike spaces or cysts that frequently contain mucus or collagen; most common in salivary glands and skin.
References in periodicals archive ?
Salivary adenoid cystic carcinoma in Denmark 1990-2005: Outcome and independent prognostic factors including the benefit of radiotherapy: results of the Danish Head and Neck Cancer Group (DAHANCA).
Patterns of spread of head and neck adenoid cystic carcinoma. Clin Radiol 2015; 70: 644-53.
Lymph node involvement by direct extension in adenoid cystic carcinoma. Absence of classic embolic lymph node metastasis.
Woodland, "Adenoid cystic carcinoma of Bartholin's gland: A review of the literature and report of a patient," Gynecologic Oncology, vol.
MYB driver mutations associated with oncogenesis have been confirmed in several types of malignancies including leukemias and adenoid cystic carcinomas [21].
Asian studies, particularly those conducted in Japan, India and Pakistan report over 80% of all maxillofacial malignancies as squamous cell carcinoma, followed by adenoid cystic carcinoma and mucoepidermoid carcinoma.20,21,22
Zhong et al., "Clinicopathologic and prognostic factors in adenoid cystic carcinoma of head and neck minor salivary glands: A clinical analysis of 130 cases," American Journal of Otolaryngology, vol.
Another study conducted by Gill et al17 show pleomorphic adenoma as the commonest tumor 61.74% followed by warthin tumor 4.49%, hemangioma 2.11%, monomorphic adenoma 0.53% and myoepithelioma 0.26%, whereas the commonest malignant tumor was mucoepidermoid carcinoma 15.30% followed by adenoid cystic carcinoma 5.28%, carcinoma exploemorphic adenoma 1.32%, acinic cell carcinoma 1.00% and salivary duct carcinoma as 0.53%.
Regarding the clinical aspects, all benign tumors were nodules, whereas malignant tumors were nodules in 19 cases (11 cases of adenoid cystic carcinoma, four cases of mucoepidermoid carcinoma and four cases of acinic cell carcinoma) and ulcerated nodules in five cases (three cases of adenoid cystic carcinoma, one case of mucoepidermoid carcinoma and one case of acinic cell carcinoma).
Mrs Sherwood was diagnosed with adenoid cystic carcinoma in the base of her skull in 2008 after suffering problems with double vision.
Adenoid cystic carcinoma (ACC) arising in the breast is an uncommon primary tumour accounting for 0.1% of all breast malignancies.