adenocarcinoma in situ

Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.

ad·e·no·car·ci·no·ma in si·'tu

a noninvasive, abnormal proliferation of glands believed to precede the appearance of invasive adenocarcinoma; reported in the endometrium, breast, large intestine, cervix, and other sites.

adenocarcinoma in situ

a localized growth of abnormal glandular tissue that may become malignant. However, the abnormal cells do not extend beyond the basement membrane. It is most common in the endometrium and in the large intestine.

ad·e·no·car·ci·no·ma in si·tu

(adĕ-nō-kahr-si-nōmă in sitū)
Noninvasive, abnormal proliferation of glands believed to precede the appearance of invasive adenocarcinoma.

adenocarcinoma in situ

Abbreviation: AIS
A localized cluster of malignant appearing cells found in a gland but not yet spreading outside the basement membrane of the gland.
See also: adenocarcinoma
References in periodicals archive ?
Adenocarcinoma in situ will typically be a pure ground-glass nodule and MIA will have a predominant ground-glass component with a solid component that will typically be 5 mm or less in size.
Adenocarcinoma in situ with collapse may be difficult to distinguish from the acinar pattern.
Clinicopathologic characteristics of adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA) and lepidic predominant (LPD) adenocarcinoma of the lung (LAC): Memorial Sloan Kettering Cancer Center Experience.
Errors and Deferrals in Frozen Section (FS) Diagnoses of Adenocarcinoma In Situ (AIS), Minimally Invasive Adenocarcinoma (MIA), and Invasive Adenocarcinoma (IA) FS Diagnosis Correct Diagnosis Cases, No.
Management and follow-up of patients with adenocarcinoma in situ of the uterine cervix.
Adenocarcinoma in situ of the uterine cervix: a clinicopathologic study of 36 cases.
Conservative management of adenocarcinoma in situ of the cervix.
Adenocarcinoma in situ ofthe cervix: clinicopathologic observations of 11 cases.
Adenocarcinoma in situ of the cervix: significance of cone biopsy margins.
Symposium part I: adenocarcinoma in situ, glandular dysplasia, and early invasive adenocarcinoma of the uterine cervix.