The researchers found that in a generalized additive model
, at annual surgeon procedure volumes of 18.2 and 18.1 procedures per year, the occurrence rates of vocal cord paralysis (VCP) and hypoparathyroidism began to decrease, respectively.
For the additive model
, the 17 significant SNPs (p<0.001) were distributed over 15 BTA containing 6 annotated genes, including LOC101903200, poly (ADP-ribose) polymerase family member 4 (PARP4), glycoprotein A33 (GPA33), NAD kinase (NADK), phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 (PREX2), and FERM domain containing 4B (FRMD4B).
Chi-squared test with 95% confidence interval identified two genes in the set of studied genes, whose SNP allele and genotype frequency difference in women with miscarriage and control group is statistically significant--TLR9 (p < 0.0001 for both multiplicative and additive models
of inheritance) (Tables 5 and 6) and IL-10 (p = 0.0003 for multiplicative model of inheritance and p = 0.001 for additive model
of inheritance) (Tables 15 and 16).
There was a significant association between the PD-L1 SNP rs4143815 and T1DM susceptibility in the additive model
(OR 0.50; P = 0.003), dominant model (OR 0.31; P = 0.012), and the recessive model (OR 0.46; P = 0.028).
Statistical power analysis indicated that the rs5370 locus had strong power (0.689--for dominant model; 0.956--for recessive model; and 0.991--for additive model
Generalised Additive Model
(GAM) mean fitted surfaces are a powerful exploratory and predicting tool that accounts for trends in space and can produce results as good as the more traditional methods (Drexler and Ainsworth 2013).
After correction for multiple testing, the SNP rs6265 was significantly associated with adiponectin under an additive model
(P = 0.02 and 0.024, resp.) after adjustment for age, gender, and BMI or obesity statuses.
Thus, the additive model
considered a total of 13 terms (an intercept, gene expression, 9 TO, RAS, and p53).
The final additive model
is hence the sum of all selected base-learner fits.
is just opposite to multiplicative model.
Genotypes were allotted code of 0/1/2 rendering the number of minor alleles under an additive model
In particular, the author emphasizes the project in Saraguro, Ecuador, which offers the population an additive model
for the acquisition of Quechua as an L2, enabling the people who live in this community to learn their heritage language.