AP1G2

(redirected from adaptor-related protein complex 1, gamma 2 subunit)

AP1G2

A gene on chromosome 16q23 that encodes a large subunit of the heterotetrameric, trans-Golgi, clathrin-associated adaptor-related protein complex AP-1, which is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. The vesicles are involved in endocytosis and Golgi processing; AP complexes recruit clathrin to membranes and recognise sorting signals within the cytosolic tails of transmembrane cargo molecules. AP1G2 may function in protein sorting in endosomes or multivesicular bodies.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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