ADAPT

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Neurology Alzheimer's Disease Anti-Inflammatory Prevention Trial. A prevention trial which investigated whether inflammation is linked to the neurodegenerative changes of Alzheimer's disease and, if so, whether NSAIDs—e.g., naproxen and celecoxib—provide any benefit
Psychiatry Adolescent Depression Antidepressant and Psychotherapy. A clinical trial that compared healthcare outcomes of treatment with selective serotonin reuptake inhibitors (SSRIs) plus cognitive behaviour therapy (CBT) versus SSRI alone in adolescents with major depression.
Conclusion The SSRI + CBT group was more expensive than the SSRI-only group and no more cost-effective. There was an average decrease in suicidal thoughts and self-harm and no significant increase in disinhibition, irritability and violence compared to baseline
Rheumatology Arthritis, Diet and Activity Promotion Trial. A clinical trial that queried the effect of lifestyle modification on physical function, pain, and disability in obese, sedentary older adults with knee OA
References in periodicals archive ?
Natural selection for adaptedness probably caused cold resistance in high-altitude Peruvian maize, resistance to rust (caused by Puccinia sorghi Schw.) in high-altitude Mexican maize, resistance to leaf blight (caused by Helminthosporium spp.) in tropical Colombian maize, and long mesocotyls of certain Hopi maize cultivars (Mangelsdorf, 1974).
The results pertain to topics dealing with the distribution of genotypes across the landscape, niche breadth, the effects of a changing climate on adaptedness of populations, and reforestation in a variable climate.
Just as the nature and proper role of the political entity cannot be comprehended without understanding the individuals it ultimately serves (failing this, regimes devolve into unstable tyranny), so too the nature of species cannot be grasped apart from seeing them in terms of the individual organisms whose adaptedness they serve.
The absolute performance level for any trait is bound to be tied to a perplexing array of environmental variables such as temperature, food quality, and density, as well as the degree of adaptedness of the population to the particular conditions used for measurement.
Different variations will be transmitted at different rates depending upon their adaptedness to the locally prevailing circumstances (which is what selection means).
The legal system thus functions on the basis of an approximate adaptedness of contemporary motivational patterns and normative self-understandings to the individualizing logic of expertly determined categories of individual motive and competence.
In the parlance of modern evolutionary psychology, these would be "domain specific algorithms" (or modules) showing a high degree of design adaptedness - perhaps we should always talk of "moral senses" in the plural.
The mind was geared to solve those problems in optimally efficient ways in a relatively stable hunter-gatherer ecology--the "environment of evolutionary adaptedness," or EEA.
Health and adaptedness. Theoretical Medicine, 14, 295-303.
If having the mental machinery to solve a particular information processing task would have been adaptive for our ancestors (i.e., if the hypothesized phenotype fits the formal definition of an adaptation; see Table 1), and if further (empirical) tests reveal that performance is enhanced in modern humans when information is presented in a format that would have been likely in the environment of evolutionary adaptedness (EEA; that is, the ancestral environment), then the mental machinery responsible for solving the task can be considered to be a bona fide mental module.