adapalene


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adapalene

 [ah-dap´ah-lēn]
a synthetic analogue of retinoic acid used topically in the treatment of acne vulgaris.

adapalene

A retinoid-like drug used externally in the treatment of ACNE. The drug should not be used during pregnancy. A brand name is Differin.
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Other studies show that adapalene 0.1% or 0.3% combined with benzoyl peroxide 2.5% reduced scar formation and scar severity compared with vehicle during 6 months of therapy in patients with active inflammatory acne and scarring.
She reported on 67 adolescents and adults with mainly moderate facial acne randomized to treat half their face with adapalene 0.3%/benzoyl peroxide 2.5% gel (Epiduo Forte) and the other half with the product's vehicle daily for 6 months.
A trial by Shi et al15 showed that adding adapalene to 2% ketoconazole in the treatment of PV increased the efficacy to 92% as compared to 72% with 2% ketoconazole alone.
Adapalene is the least irritating and most readily available, since you don't need a prescription, though it isn't as potent as tretinoin."
In announcing approval of adapalene gel 0.1 percent as an OTC product, the FDA cited as a major factor in the regulatory decision the opportunity to afford acne patients greater access to retinoid therapy.
The efficacy, safety and tolerability of adapalene versus benzoyl peroxide in the treatment of mild acne vulgaris: a randomized trial.
This launch of the company's AB rated generic version of Epiduo (adapalene and benzoyl peroxide) Gel, 0.1%/2.5% follows the US Food and Drug Administration's (FDA) approval.
Our aim was to evaluate the efficacy and safety of KRT in a comparative study between the conventional treatment using adapalene and local antibiotics and this treatment combined with KRT therapy.
Phase Ib/IIa clinical study of Adapalene and Clindamycin combination hydrochloride gel for acne vulgaris (moderate to severe acne) has been completed and positive results therefrom which meet pre-specified endpoints has been attained.
FORT WORTH -- Dermatology products maker Galderma Laboratories LP has partnered with actress Ashley Benson, best-known for her role as Hanna Marin in the television series "Pretty Little Liars," to celebrate the launch of Differin Gel (adapalene gel 0.1%), an over-the-counter treatment for acne.
WAILEA, HAWAII -- The Food and Drug Administration's approval of adapalene gel 0.1% as an over-the-counter treatment for acne is a potential game changer that could lead to revision of guideline-recommended treatment algorithms, according to Lawrence F.