adamantinoma


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ameloblastoma

 [ah-mel″o-blas-to´mah]
a locally invasive, highly destructive tumor of the jaw; called also adamantinoma.
pituitary ameloblastoma craniopharyngioma.

ad·a·man·ti·no·ma

(ad'-ŏ-man-ti-nō'mă),
1. A low-grade malignant tumor of long bones (predominantly tibia) marked by a proliferation of nests of basaloid cells with palisading at the periphery. Compare: ameloblastoma.
2. A rare, slow-growing but locally aggressive tumor; its histogenesis remains controversial. Approximately 200 cases have been reported since it was first described in 1913. The tumor occurs almost exclusively in the long bones; tumors in the tibia account for more than 80% of cases. The diaphysial region is the area most commonly affected. The histiologic features of adamantinomas have many variations that are present not only among patients but also among different areas of the same tumor. Metastases occur in approximately 15-20% of patients and typically appear in the lungs and local lymph nodes.

adamantinoma

An extremely rare, generally indolent malignant epithelial tumour, which arises almost exclusively in the tibia or fibula in the second to fifth decade in life.

Clinical findings
Swelling, pain, developing over months to years.

Imaging
Eccentric, well-circumscribed, and lytic lesion on plain films.

DiffDx
Osteofibrous dysplasia, fibrous dysplasia, aneurysmal bone cyst, chondromyxoid fibroma, chondrosarcoma.

Management
Wide resection or amputation.

Prognosis
Excellent; overall survival is 85% at 10 years, but lower without adequate margins. Metastases are rare at presentation but may occur in up to 30% of patients during the disease course.

am·e·lo·blas·to·ma

(am'el'ō-blas-tō'mă)
A benign odontogenic epithelial neoplasm; it behaves as a slowly growing expansile radiolucent tumor, occurs most commonly in the posterior regions of the mandible, and has a marked tendency to recur if inadequately excised.
[ameloblast + G. -oma, tumor]
References in periodicals archive ?
Congenital melanocarcinoma, melanotic adamantinoma, retinal anlage tumor, progonoma, and pigmented epulis of infancy.
There have been no definitive guidelines for a treatment of adamantinoma. The preferred treatment is surgical management with wide margins, reconstruction if necessary and possible, or amputation [1].
To our knowledge, this is the oldest case in English literature of a patient with adamantinoma of the femur.
The term 'adamantinoma' was introduced by Malassez in 1885 to denote the epithelial odontogenic tumor which had been recognized by Cuzak in 1827.
Ghosh, "Adamantinoma of the upper jaw," The American Journal of Pathology, vol.
Bir calismada izlemde tekrarlanan biyopside adamantinoma saptanmasi nedeniyle butun osteofibroz displazi tanili olgulara ekstraperiostal eksizyon onerilmektedir (11).
El ameloblastoma es un tumor odontogenico de origen epitelial, polimorfico deformante e invasivo con patrones clinicos de malignidad local y altamente recurrente, (1) Fue reportado inicialmente por Falkson y Malassez en 1885 denominandolos adamantinoma -- epitelioma, debido a que histologicamente deriva de los componentes de la odontogenesis como remanentes de la lamina dental, restos epiteliales de Malassez, epitelio reducido del esmalte y celulas basales.
Later on, Mallasez introduced the term "adamantinoma" and Churchill finally named it as ameloblastoma in 1934.3 It represents 1% of all the tumours of mandibular and maxillary region and approxi-mately 10% of all odontogenic mandibular tu-mours.4
The lesion was further described in 1885 by Malassez, who called it an adamantinoma. The term ameloblastoma was coined by Ivy and Churchill in 1934 The term giant ameloblastoma should be reserved for lesions that are truly large and that cause gross asymmetry and regional dysfunction.
We report a case of a tibial adamantinoma that was treated with a limb salvage procedure utilizing an intercalary tibial allograft and a free vascularized osteocutaneous graft of the fibula.
Keratin and Vimentin Expression in Carcinomas and Mesenchymal Tumors Carcinomas That Frequently Express Both Renal cell carcinoma Anaplastic thyroid carcinoma Endometrial carcinoma Thyroid carcinoma Sarcomatoid carcinoma Mesothelioma Myoepithelial carcinoma Metaplastic breast carcinoma Carcinomas That Rarely Express Both Breast carcinoma Ovarian carcinoma Gastrointestinal carcinoma Lung small cell carcinoma Lung non-small cell carcinoma Prostate carcinoma Mesenchymal Tumors That Frequently Express Both Synovial sarcoma Desmoplastic small round blue cell tumor Epithelioid sarcoma Epithelioid angiosarcoma Malignant rhabdoid tumor Leiomyosarcoma Chordoma Adamantinoma Table 4.