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[EC class 2.3] An enzyme catalyzing the transfer of an acyl group from an acyl-CoA to any of various acceptors.
Synonym(s): transacylase.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
BryP is a discrete acyltransferase domain which loads malonate units onto the ACP domains located in the elongation modules.
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that catalyses the formation of cholesterol esters from cholesterol and fatty acyl-coenzyme A.
They also had markedly altered protein components of HDL, including elevated levels of haptoglobin, hemoglobin, apo A-1, myeloperoxidase, and hemopexin (in plasma but not in HDL) and lower lecithin cholesterol acyltransferase (LCAT).
As in the case of nobiletin, natsudaidain inhibits the production of triacylglycerol (Figure 3A) by decreasing diacylglycerol acyltransferase activity in hamster sebocytes (data not shown).
More recently, the SRRC researchers have uncovered vital information about two of the plant's most pivotal enzyme players for determining the types and amounts of fatty acids that accumulate in oil: DGAT1 and DGAT2--short for diacylglycerol acyltransferase type 1 and type 2.
The transgenes include those coding for the enzymes which play important roles in the formation of the fatty acids and in the incorporation of the fatty acids into triacylglycerols (TAG), such as ACCase, KAS, acyl-ACP thioesterase, desaturase, elongase, and acyltransferase. Various sources have been utilized including related Brassica species, other higher or lower plants, yeast, bacteria, and mammals.
Serum total cholesterol and high-density lipoprotein cholesterol concentrations and lecithin-cholesterol acyltransferase (LCAT) activity were measured before randomization and at treatment end-point.
The agent pactimibe is an acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.
The new nonstatin drug classes that he expects to dominate discussions of lipid-lowering drugs in the next few years are cholesteryl ester transfer protein (CETP) inhibitors, peroxisome proliferator-activated receptor (PPAR) agonists, and acyl coenzyme A:cholesterol acyltransferase (ACAT) inhibitors.
Calgene LLC (Davis, CA) has patented nucleic acid sequences encoding for acyl-CoA:cholesterol acyltransferase (ACAT) related proteins, wherein ACAT-like protein is active in the formation of a sterol ester and/or triacylylgycerol from a fatty acyl-CoA and sterol and/or diacylglycerol substrates.
Epidemiological correlates of high density lipoprotein subfractions, apolipoproteins A-I, A-II, and D, and lecithin cholesterol acyltransferase. Effects of smoking, alcohol, and adiposity.