acyl-CoA

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ac·yl-CoA

(as'il),
Condensation product of a carboxylic acid and coenzyme A; metabolic intermediate of importance, notably in the oxidation and synthesis of fats.
Synonym(s): acyl-coenzyme A

ac·yl-CoA

(as'il-kō-ā)
Condensation product of a carboxylic acid and coenzyme A; metabolic intermediate of importance, notably in the oxidation and synthesis of fat.
References in periodicals archive ?
The nine target genes were acyl-CoA synthetase long-chain family member 6 (ACSL6), apolipoprotein A-I (APOA1), PLTP, GK, CPT2, aquaporin 7 (AQP7), acyl-Coenzyme A oxidase 1 palmitoyl (ACOX1), ACOX2, and FABP4.
Very-long-chain acyl-coenzyme A dehydrogenase deficiency in a child with recurrent myoglobinuria.
Reversal of severe hypertrophic cardiomyopathy and excellent neuropsychologic outcome in very-long-chain acyl-coenzyme A dehydrogenase deficiency.
In particular, think of medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency, which is the most common of the inherited errors of fatty acid metabolism.
This hormone increases insulin sensitivity, increases expression of the muscle insulin receptor, and decreases intramuscular lipids and the fatty acyl-coenzyme A molecules that can cause insulin resistance, Dr.
Specific examples of current projects include acyl-coenzyme A diacylglycerol acyltransferase (DGAT), 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD), desaturases, and a family of histone deacetylases (HDACs).
3]H]-palmitato para la deteccion de trastornos tales como la deficiencia de acil-CoA deshidrogenasa de cadena media (MCAD, por la sigla en ingles de medium-chain acyl-coenzyme A dehydrogenase) en la que la [beta]-oxidacion se encuentra detenida en los sustratos con ocho atomos de carbono.
These include isoforms of the facilitated glucose transporters (GLUT), the glutamate transporters, cationic amino acid transporters, fatty acid transporters, fatty acid binding proteins, aldolases, acyl-Coenzyme A oxidases, long-chain acyl-CoA synthetases, acylglycerol-3-phosphate O-acyltransferases, phosphatidic acid phosphatases, and suppressor of cytokine signaling genes.
For example, medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency is one of the disorders that can be screened for using this technique.

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