acyl CoA

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acyl CoA

/ac·yl CoA/ (a´sil ko-a´) acyl coenzyme A.


1. an organic radical derived from a fatty acid by removal of the hydroxyl group.
2. generic term for fatty acid groups.

acyl carrier protein
ACP; a carrier protein molecule which is part of the fatty acid synthesizing enzyme complex in non-mammalian systems and which carries acyl groups.
acyl CoA
thioester of coenzyme A and a fatty acid of unspecified, but usually more than 14 carbon length.
acyl CoA dehydrogenase deficiency
lack of the first enzyme of beta-oxidation, acyl CoA dehydrogenase, a flavoprotein which catalyzes the removal of two hydrogens from the acyl chain.
References in periodicals archive ?
The peroxisome proliferator (PP) response element (PPRE) upstream of the human acyl CoA oxidase gene is inactive in a sample human population: significance for species differences in response to PPs.
Luca Picone-Chiodo, who was at high risk of having MCAD (Medium-chain acyl CoA dehydrogenase) a genetic condition that affects the metabolism, died at his family home in Huddersfield on October 16, 2009.
cite the finding of an inactive PP response element upstream of the acyl CoA oxidase gene in a sample human population (15) as additional evidence for why humans may be less responsive than rodents to PPs.
Diagnosis of medium chain acyl CoA dehydrogenase deficiency by measurement of cis-4-decenoic acid in dried blood spots.