acute self-limited colitis
acute self-limited colitisTransient colonic inflammation with features that overlap idiopathic bowel disease, which presents with bloody diarrhoea and resolves usually within 2–4 weeks without residual inflammation or recurrent symptoms. It is a diagnosis of exclusion—i.e., the absence of histologic criteria for diagnosing IBD. ASLC is presumed to have an infectious aetiology—in 50% of cases a specific pathogen is identified; bacterial pathogens include: Campylobacter, Shigella, Salmonella species E coli O157:H7, as well as viruses and parasites (e.g., Giardia).
Diversion colitis, preparations for scoping—e.g., Fleet’s enema, herbal cleansers.
Histologic criteria, acute self-limited colitis
Acute inflammation generally confined to the lamina propria
• Patchy or diffuse;
• Crypt abscesses may be present;
• Neutrophils in the crypt epithelium.
No chronic changes
• Minimal to no crypt distortion or dropout;
• No to only mild chronic inflammation of the lamina propria;
• Severe cases may be ulcerated, haemorrhagic and have microthrombi.