HBBM was intended to be the first of two clinical trials to support registration of the compound for monotherapy in acute schizophrenia
SAN FRANCISCO -- Lurasidone, a novel antipsychotic agent, appears to be safe and effective in acute schizophrenia
and at least as good as ziprasidone in stable outpatients with schizophrenia or schizoaffective disorder, according to conclusions of several phase I and phase III clinical trials.
Results: The clinical depression seen in acute schizophrenia
and primary depression differed significantly from that seen in chronic schizophrenia.
Chris, 30, claims he suffered acute schizophrenia
as a result of being hypnotised by McKenna at the Swan Theatre in his home town of High Wycombe, Bucking-hamshire, four years ago and is suing the star for pounds 250,000.
dba Pioneer Behavioral Health (Nasdaq:PIHC), a leading provider of inpatient, outpatient and online behavioral health services, announced today that its research unit, Pioneer Pharmaceutical Research, has won two new contracts with major pharmaceutical companies to conduct clinical research trials for treatment of bipolar disorder and acute schizophrenia
The approval is based on acute schizophrenia
trials in which SAPHRIS (5 mg twice daily) demonstrated statistically significant efficacy versus placebo and acute bipolar I disorder studies in which SAPHRIS (10 mg twice daily) demonstrated statistically significant reduction of bipolar mania symptoms versus placebo.
A previous randomized, double-blind, placebo-controlled trial in 182 patients with acute schizophrenia
found that asenapine was effective and well tolerated, compared with placebo, with one arm of the study randomized to risperidone (Risperdal) therapy to verify the assay sensitivity (J.
The court heard he was suffering from acute schizophrenia
at the time.
In the news release, FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia
, issued 30-Jul-2009 by Schering-Plough Corporation over PR Newswire, the first paragraph, first sentence, should read "in favor of use" rather than "in favor of youth" as incorrectly transmitted by PR Newswire.
Keith said, warning that intense treatments do not work with acute schizophrenia
But he was transformed into a giggling, gibbering wreck suffering from acute schizophrenia
- and is now suing the star for pounds 250,000.
This six-week, randomized, double-blind, multicenter, placebo-controlled trial, involving 180 patients with acute schizophrenia
, evaluated a single fixed dose of lurasidone 80 mg/day versus placebo.