Acute pyelonephritis: comparison of diagnosis with 99mTc DMSA SPECT, spiral CT, MR imaging and power Doppler US in an experimental pig model.
Hewitt and his associates noted "there is an almost universally held view in the literature and publicized evidence-based clinical guidelines that early aggressive therapy of
acute pyelonephritis in children, particularly very young children, is essential to reduce the subsequent frequency and degree of scarring."
Of 63 women aged 18 years and older who had been hospitalized with
acute pyelonephritis between January 1982 and December 1992, 29 (46%) were found to have renal scars 10 or more years later on dimercaptosuccinic acid scans, while 34 (54%) did not.
Therefore, a retrospective chart review of patients hospitalized with the diagnosis of
acute pyelonephritis was performed to determine its clinical utility.
"If someone comes in with
acute pyelonephritis and preterm labor, you don't want to use tocolytics such as terbutaline because terbutaline itself is associated with increased risk of pulmonary edema, which in turn can result in adult respiratory distress syndrome.
piperacillin/tazobactam in the treatment of complicated urinary tract infections, including
acute pyelonephritis, in hospitalized adults."
Evaluation of the use of DMSA in culture negative
acute pyelonephritis. Indian Pediatr.
While this study may be criticized because it relied on voided urines for culture, the clinical diagnosis of
acute pyelonephritis is hard to deny, and all patients, including control patients, were studied in the same way.
Escherichia coli usually cause a child's first infection (were responsible for more than 90% of cases of
acute pyelonephritis in infants and children), but other gram-negative bacilli like klebsiella and enterococci may also cause infection.
Acute pyelonephritis is estimated to occur in 1 % to 2% of all pregnancies., Prompt antimicrobial therapy is essential to prevent the well-described hemodynamic, hematologic, and renal complications of urosepsis.
This poster will focus on clinical and microbiological response at test of cure in secondary efficacy populations from the pivotal Phase 2/3 clinical trial for the treatment of cUTIs, including
acute pyelonephritis, which demonstrated non-inferiority to piperacillin/tazobactam in patients with cUTI, including AP.
Gilstrap LC, Cunningham FG, Whalley PJ:
Acute pyelonephritis in pregnancy: An anterospective study.
