acute generalized exanthematous pustulosis


Also found in: Acronyms.

acute generalized exanthematous pustulosis

Abbreviation: AGEP.
A rare but severe allergic reaction to a drug, characterized by a widespread pustular rash, fever, and a high white blood cell count. It usually resolves within a few weeks after one stops taking the drug that caused the reaction.
See also: pustulosis
References in periodicals archive ?
A diagnostic challenge: acute generalized exanthematous pustulosis or pustular psoriasis due to terbinafine.
Systemic involvement of acute generalized exanthematous pustulosis: a retrospective study on 58 patients.
Acute generalized exanthematous pustulosis (AGEP) is an uncommon skin eruption characterized by superficial nonfollicular aseptic pustules.
Viboud et al., "Risk factors for acute generalized exanthematous pustulosis (AGEP)-results of a multinational case-control study (EuroSCAR)," British Journal of Dermatology, vol.
Acute generalized exanthematous pustulosis. Analysis of 63 cases.
A systemic reaction to patch testing for the evaluation of acute generalized exanthematous pustulosis. Arch Dermatol, 2003; 139: 1181-1183.
Thirumoorthy, "Acute generalized exanthematous pustulosis: analysis of cases managed in a tertiary hospital in Singapore," International Journal of Dermatology, vol.
Ioulios et al.18 in their review of literature of the spectrum of cutaneous reactions associated with calcium antagonists, have described about flushing, peripheral edema, gingival hyperplasia, facial telangiectasia, photosensitivity reactions, psoriasiform eruptions, acute generalized exanthematous pustulosis, hypersensitivity syndrome, exfoliative dermatitis and Stevens-Johnson syndrome, subacute cutaneous lupus erythematosus, pemphigus and pemphigoid, erythromelalgia, gynecomastia and oral ulcers.18
Acute generalized exanthematous pustulosis (AGEP) is a fairly rare condition, with a reported incidence of one to five cases per million people per year.
T-cell involvement in drug induced acute generalized exanthematous pustulosis. J Clin Invest 2001; 107: 1433-41.
Mancini reviewed common exanthems, and many that aren't so common, paying special attention to five of the newer or atypical exanthems: acute generalized exanthematous pustulosis (AGEP), Arcanobacterium haemolyticum, Gianotti-Crosti syndrome, papular-purPuric gloves and socks syndrome, and unilateral laterothoracic exanthem.
Severe cutaneous adverse reaction (SCAR) is T-cell-mediated delayed-type hypersensitivity, including Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/ TEN), drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS), and acute generalized exanthematous pustulosis (AGEP).

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