acute fatty liver of pregnancy


Also found in: Acronyms, Wikipedia.

Acute Fatty Liver of Pregnancy

A rare (1:10,000–15,000) idiopathic complication of pregnancy, most often affecting primiparas with male infants or twins, variably associated with pre-eclampsia.
Clinical findings Onset after 35th week—occasionally as early as the 13th week—possibly progressing to fulminant hepatic failure with jaundice, encephalopathy, DIC, death.
Prognosis ±20% mortality
Management Terminate pregnancy

acute fatty liver of pregnancy

 Fatty liver of pregnancy, see there.
References in periodicals archive ?
Physicians must be diligent in diagnosing acute fatty liver of pregnancy, and be prepared for its high morbidity and mortality," said Dr.
He and his associates assessed the clinical presentations and outcomes of all 16 women treated for acute fatty liver of pregnancy (AFLP) at three tertiary-care centers in Ohio and Kentucky between 1993 and 2003.
Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency.
The molecular basis of pediatric long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with acute fatty liver of pregnancy.
20 The current study indicates very low frequency of acute fatty liver of pregnancy (1.
Idiopathic acute fatty liver of pregnancy in 12 patients.
Maternal mortality was highest 35% in acute fatty liver of pregnancy which reduces to 18% if unbooked with uncorrected disseminated intravascular coagulation are excluded.
Wei Q (14) found all cases of acute fatty liver of pregnancy presented with a prodrome of nausea, vomiting, malaise and jaundice.
Acute fatty liver of pregnancy and sepsis are rarely seen etiologic factors, which might eventually result in the death of the patient.
Patients with a history of primary or secondary immune thrombocytopenia (ITP), thrombocytopenia of any etiology preceding pregnancy, or any reason for thrombocytopenia other than uncomplicated pregnancy itself like Preeclampsia/eclampsia, acute fatty liver of pregnancy are generally not considered to have gestational thrombocytopenia.
INCIDENCE: Out of 30 patients, 10 had preeclampsia, 4 had HELLP, 2 diagnosed with acute fatty liver of pregnancy.

Full browser ?