activity grading

ac·tiv·i·ty grad·ing

(ak-tiv'i-tē grād'ing)
Incrementally changing the process, tools, materials, or environment of a given activity to increase or decrease performance demands gradually, and ultimately to ensure best performance.
Synonym(s): sport-specific training.
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--Tegner activity grading scale (from 0 to 10)--a system for evaluating the degree of impairment, disability, and handicap of the patient with an ACL injury including functional score, activity grading, stability testing, and measurements of performance and strength, where 0 indicates retirement, while 10 allows professional sport activities [16].
The diagnostic value of FT for fibrosis staging and of AT for activity grading was similar to those reported previously (8,10-18) with areas under the ROC curves of 0.80 (0.02) for the diagnosis of F2F3F4 and 0.78 (0.02) for the diagnosis of A2A3 (Fig.
In 154 of 537 patients (29%), there was a significant discordance at baseline between FT-AT and biopsy results for fibrosis staging or activity grading. This occurred in 63 patients (12%) for fibrosis staging only, in 67 patients (12%) for activity grading only, and in 24 patients (4.5%) for both.
Compared with patients who did not have false-negative activity grading based on biopsy (n = 483), patients who did have false-negative activity grading based on biopsy (n = 54) had a smaller biopsy size [13.5 (0.7) vs 16.4 (0.3) mm; P = 0.002], fewer portal tracts [12.9 (0.8) vs 15.9 (0.4); P = 0.03], poorer quality biopsies (17% vs 32%; P = 0.02), more frequent liver steatosis (64% vs 40%; P <0.001), higher ALT serum activity [203 (17) vs 99 (4) U/L; P <0.001], higher serum ferritin [502 (72) IU/L (n = 31) vs 275 (27) IU/L (n = 135); P = 0.005], and were more frequently male (76% vs 58%; P = 0.01).
In 209 of 537 patients (39%), there was a significant discordance at baseline between FT-AT and biopsy results for fibrosis staging or activity grading. This occurred in 78 patients (14%) for fibrosis staging only, in 91 patients (17%) for activity grading only, and in 24 patients (7.4%) for both.
According to the risk factors, the independent endpoints, and the follow-up, the causes of failure among the 54 cases discordant by only 1 or 1.5 stages or grades were considered highly attributable to FT-AT in 1 case (hemolysis), moderately attributable to FT-AT in 1 (isolated low [[alpha].sub.2] -macroglobulin), highly attributable to biopsy in 2 (false negative for fibrosis staging), and moderately attributable to biopsy in 14 (mostly falsely negative for activity grading).