Generally, pyoderma gangrenosum is known to be common among patients with systemic diseases such as inflammatory bowel diseases, polyarthritis, diverticulosis, paraproteinaemia, myeloma, leukaemia, active chronic hepatitis, and Behcet syndrome.
It is mostly idiopathic; nevertheless, underplaying immunological anomalies have been recognized.2 Fifty percent of the patients have underlying systemic diseases such as inflammatory bowel diseases, polyarthritis, diverticulosis, paraproteinaemia, myeloma, leukaemia, active chronic hepatitis, and Behcet syndrome.1 There are four known variants of pyoderma gangrenosum; ulcerative, pustular, bullous and superficial.3
in his study found that the mean liver zinc concentrations were 3.83 +- 1.86, 1.86 +-0.92, 1.14 +- 0.68 and 3.74 +- 1.81mumol/g among control group,
active chronic hepatitis, cirrhosis and persistent chronic hepatitis groups respectively.5
