activated lymphocyte


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activated lymphocyte

A lymphocyte stimulated by exposure to a specific antigen or by macrophage processing so that it is capable of responding to a foreign antigen by neutralizing or eliminating it.
See also: lymphocyte
References in periodicals archive ?
At the same time, in the presence of an inhibitor, we registered a marked increase in IDO transcription in hASC incubated with activated lymphocytes in contactless conditions (Figure 3(b)).
It is implicated that the source for the high concentrations of the alpha-chain of the soluble interleukin-2 receptor is activated lymphocytes. Lastly hepatoslenomegaly, increased bilirubin and liver enzyme along with neurological symptoms are the consequence of organ damage due to infiltration by activated lymphocytes and histiocytes.
Regarding the new metabolic demands of activated lymphocytes, glucose is initially retained in the cell by phosphorylation into glucose 6-phosphate by hexokinases (HKs) [2].
It has been shown that glycosylation changes occur in activated lymphocytes [26], and differences in sialylation as well as in expression of O-glycans are related to control of T-cell activation [ 30].
Finding Mollaret-like cells admixed with activated lymphocytes may be a useful, readily-available test that provides supportive evidence of viral encephalitis in the appropriate clinical setting, until more definitive tests are available.
Selective binding with S1PR1 receptors is believed to inhibit a specific sub set of activated lymphocytes from migrating to sites of inflammation.
AUBAGIO (Teriflunomide) is an immunomodulator with anti-inflammatory properties and may involve a reduction in the number of activated lymphocytes in the central nervous system (CNS).
In the laboratory, a Giemsa stain of a smear prepared from the patient's blood showed activated lymphocytes. A complete blood count showed thrombocytosis (632 x [10.sup.3]/[micro]L), but all other hematologic parameters were within the normal range.
The humanised monoclonal antibody, vatelizumab, is aimed at VLA-2, a collagen-binding integrin expressed on activated lymphocytes.
The possible immunopathologic mechanism of HLH might be excessive production of Th1 cytokines, such as gamma-interferon, tumor necrosis factor-alpha, interleukin-1, or interleukin-6, from activated lymphocytes or monocytes (1,2).
According to the company, AUBAGIO is an immunomodulator with anti-inflammatory properties, which could possibly reduce the number of activated lymphocytes in the central nervous system.
Although the exact mechanism of action for Aubagio is not fully understood, it may involve a reduction in the number of activated lymphocytes in the central nervous system (CNS).

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