In consideration for the acquisition of Activate
(the "Transaction"), UMG will issue 2,333,333 Common Shares at a price of $0.30 per share.
With many more planned additions to Activate
we look forward to your support, so watch this space and get Activated!!
Low doses of the endocrine disruptor bisphenol-A and the native hormone 17beta-estradiol rapidly activate
transcription factor CREB.
Because only Cu and V showed significant vasoconstrictor activity, we determined whether or not Cu and V could activate
ERK1/2 and p38 MAPK.
The compounds used for the exposure experiments of transgenic animals were also tested in an in vitro assay to separately assess their potency to activate
ER-[alpha] or ER-[beta] using a similar reporter gene as used in the transgenic animals, only without the flanking insulator sequences (Figure 5).
The demonstration that many PCBs block SXR in humans rather than activate
it--as previously thought, based on animal models--challenges the assumption that animal models extrapolate to humans.
From these results, the scientists speculate that adding alcohol to inflamed or damaged tissue produces a situation in which a person's body temperature activates
VR1 and creates a painful, burning sensation.
Therefore, DNA damage induced by chrysotile exposure might activate
the signaling pathways leading to PIKK activation, and resultant p53 activation might contribute to the protection of cells from fatal genetic injury.
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The new research shows that these drugs, known as imidazoquinolines, appear to activate
toll-like receptor 7 (TLR7), a protein on immune cells.
Berkeley, CA, September 20, 2012 --(PR.com)-- Activate
Version 5 Customer Preview
MEHP is unique among the phthalates in its suppression of aromatase and in its ability to activate
peroxisome proliferator-activated receptors (PPARs).