dactinomycin

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dactinomycin

 [dak″tĭ-no-mi´sin]
an antitumor antibiotic of the actinomycin complex (actinomycin D), produced by Streptomyces parvulus. Used to treat rhabdomyosarcoma and Wilms' tumor in children, as well as Ewing's sarcoma, Kaposi's sarcoma, osteogenic sarcoma, soft tissue sarcomas, testicular carcinoma, and choriocarcinoma.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

dac·ti·no·my·cin

(dak'ti-nō-mī'sin),
An antineoplastic antibiotic produced by several species of Streptomyces (for example, S. parvulus).
See also: actinomycins.
Synonym(s): actinomycin D
Farlex Partner Medical Dictionary © Farlex 2012

dactinomycin

(dăk′tə-nō-mī′sĭn)
n.
An antibiotic of the actinomycin group, C62H86N12O16, isolated from bacteria and used as an antineoplastic agent in the treatment of certain cancers. Also called actinomycin D.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Actinomycin D

A relatively toxic antibiotic produced by Streptomyces spp, which is used as a chemotherapeutic.
Mechanism Inhibits DNA transcription by RNA polymerase.
Indications Rhabdomyosarcoma, Wilms’ tumour, gestational trophoblastic tumour 
Adverse effects Anorexia, nausea, vomiting, myelosuppression with pancytopenia, diarrhoea
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

dactinomycin

Oncology An antitumor antibiotic member of a class of drugs first isolated from Streptomyces, and used to treat Wilms' tumor, Ewing sarcoma, embryonal rhabdomyosarcoma, choriocarcinoma, seminoma, KS, lymphoma
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

dac·ti·no·my·cin

(dak'ti-nō-mī'sin)
An antineoplastic antibiotic produced by several species of Streptomyces (e.g., S. parvulus).
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

dactinomycin

A cytotoxic drug used to treat cancers mainly of children. Dactinomycin is an antibiotic derived from Streptomyces pavullus which causes breaks in DNA. This side effect renders it unsuitable as an antibacterial drug, but makes it useful as an anti-cancer drug. A brand name is Cosmegen Lyovac. There are other actinomycins in the group produced by Streptomyces chrysomallas .
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

dac·ti·no·my·cin

(dak'ti-nō-mī'sin)
An antineoplastic antibiotic produced by several species of Streptomyces (e.g., S. parvulus).
Medical Dictionary for the Dental Professions © Farlex 2012