actin


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actin

 [ak´tin]
a muscle protein localized in the I band of myofibrils; acting along with myosin particles, it is responsible for the contraction and relaxation of muscle fibers.

ac·tin

(ak'tin),
One of the protein components into which actomyosin can be split; it can exist in a fibrous form (F-actin) or a globular form (G-actin).

actin

(ăk′tĭn)
n.
A protein that forms the microfilaments of the eukaryotic cytoskeleton and plays an important role in cell movement, shape, and internal organization. In muscle cells, it functions with myosin to produce contraction.

Actin

One of two major muscle proteins—the other is myosin—which is an ATPase that binds to adenine nucleotides. In concert with myosin, actin is a filamentous protein responsible for muscle contraction, and has an active mechanicochemical role in cell function; it is divided into a 46-kD monomeric form, G-actin and a mature contractile form, F-actin, formed from G-actin polymers, capable of functioning in absence of myosin.

ac·tin

(ak'tin)
One of the protein components into which actomyosin can be split; it can exist in a fibrous form (F-actin) or a globular form (G-actin).

actin

A contractile protein in muscle, found in the thin filaments, to which the myosin cross-bridges bind. Actin filaments are also abundant inside all nucleated cells where they form the cytoskeleton, determining cell shape and, in the case of amoebic cells, cell movement. An actin contractile ring forms around the equator of a dividing cell at the end of MITOSIS and tightens so as to pinch the two daughter cells apart.

actin

a contractile protein found in the muscles of all animals from protozoa to vertebrates and in the MICROFILAMENTS of all cells. The energy for contraction is derived from ATP; See MYOSIN.
References in periodicals archive ?
Actin. Actin (42 kDa) is the most abundant protein in almost all types of cells and the regulation of its architecture is essential for proper muscle function (Hopkins; Pappas et al., 2010).
In the center of the two actin-poor regions, actin was observed as a spherical mass (Fig.
Osteogenic differentiation, induced by soluble factors, showed modification of the actin cytoskeleton.
When an ATP molecule binds to the myosin head, the myosin head dissociates from the actin, the ATP fluorescence at the position of the myosin increases and at the same time displacement decreases to zero (from state (1) to state (2) in Fig.
Effect of Cytochalasin D on Actin Cytoskeleton in fMLP-, LPS-, or PMA-Treated Neutrophils upon Adhesion to Fibronectin.
Procaccio et al., "Aggregation of actin and cofilin in identical twins with juvenile-onset dystonia," Annals of Neurology, vol.
The details on polarity maintenance through self-assembling actin cytoskeletal structure coupling with the dynamics of FAs, which are known to be regulated by Rho family GTPases [20, 21], have been studied extensively in relation to the key steps: protrusion at the leading edge, adhesion to the extracellular matrix via FAs, and detachment and retraction at the cell rear.
Confocal microscopy images of F-actin stained with Phalloidin showed that, in PEG 35 pretreated livers, filamentous actin associated with the membrane microfilamentous network and the pericanalicular band are kept preserved (Figure 5(a)).
At the center of the discovery is a protein called actin, which forms fibers that span the cytoplasm of cells to create the cell's cytoskeleton.
Fibers composed of a protein called actin are responsible for human cells' ability to tell right from left, researchers report in the April Nature Cell Biology.