Although some studies showed a higher PTTG expression in acromegalic
patients than in NFPA (31, 32), we noted a significantly higher expression of PTTG in NFPA (P=0.04), which was in agreement with the higher rate of invasiveness of this tumor subtype (5, 34, 35).
and other co-workers, (2014) (18,19) showed elevated IGF1 level in acromegalic
patients than normal value before treatment, and after treatment found within the normal range.
Moreover, in another study, decreases in insulin, triglyceride (TG) and fibrinogen levels together with IMT were detected as a consequence of inhibition of GH/IGF-1 secretion in acromegalic
At the moment of diagnosis, the patient showed acromegalic
signs: enlargements of hands, feet and nasal pyramid.
arthropathy: a reversible rheumatic disease.
Antisense Therapeutics, an Australian publicly traded pharmaceutical drug discovery and development company, has enrolled 24 acromegalic
patients who have been randomised to one of the two treatment regimens of dosing in the Phase II trial of ATL1103 for the growth disorder, acromegaly, it was reported yesterday.
Byrne, who died in 1783 aged just 22, was huge due to a growth disorder called acromegalic
gigantism where a person produces too much growth hormone.
(9,10) Hypertrophic articular cartilage and the growth of chondrocytes in the articular cartilage may give rise to acromegalic
Therefore, at the end ofa 12-months phase III study, pasireotide has been approved for Cushing's disease , and it is currently in phase III clinical trials for acromegalic
patients and phase II trials for neuroendocrine tumors (NETs).
Using the intubating laryngeal mask airway for ventilation and endotracheal intubation in anesthetized and unparalyzed acromegalic
Extrahypothalmic growth-hormone-releasing factor (GFR) secretion is a rare cause of acromegaly: plasma GRF levels in 177 acromegalic
patients.J Clin Endocrinol Metab 1984; 59:846-9.
To date, only one study, from Argentina, evaluated active acromegalic
patients (n=15) for oxLDL levels and oxidative stress markers in comparison with age- and gender-matched healthy controls (73).