In this study, trifluralin, acriflavine, saponin and plumbagin were used in alternate combination of two drugs against L.
For the experimental handling, the groups had been divided as follows: Group 1 received a dose each of acriflavine and saponin; Group 2 received a dose each of trifluralin and acriflavine; Group 3 received a dose each of trifluralin and plumbagin; Group 4 received a dose each of saponin and plumbagin; Group 5 received a dose each of trifluralin and saponin; and Group 6 received a dose each of acriflavine and plumbagin.
Trifluralin, acriflavine and saponin extract were purchased from Sigma.
Researchers have found that acriflavine has the previously unknown ability to halt the growth of new blood vessels.
Preliminary tests showed that mice engineered to develop cancer had no tumour growth if treated with daily injections of acriflavine.
Acriflavine stops blood vessel growth by inhibiting the function of the protein hypoxia-inducible factor (HIF)-1, which was discovered by Semenza's team in 1992.
Comparison of acridine orange, acriflavine
and bisbenzimide stains for enumeration of bacteria in clear and humic waters.
When used in conjunction with intravenous contrast agents such as fluorescein, acriflavine
, and cresyl violet, the microscope allows endoscopists to visualize the abnormal cell growth characteristic of cancerous lesions.
Determining MIC to ciprofloxacin, norfloxacin, ethidium bromide, and acriflavine
in the presence or absence of reserpine showed greater than fourfold MIC decreases in the presence of reserpine, both in the CipR-71 strain and in the two transformants obtained when chromosomal DNA was used as donor, which indicates the existence of an efflux mechanism (data not shown).