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Related to acridine: acridine dyes


a crystalline hydrocarbon, C14h10, from coal tar, used in making dyes.


A dye, dye intermediate, and antiseptic precursor (for example, 9-aminoacridine, acriflavine, proflavine hemisulfate) derived from coal tar and irritating to skin and mucous membranes; a potent mutagen.
Synonym(s): dibenzopyridine


/ac·ri·dine/ (ak´rĭ-dēn) an alkaloid from anthracene used in the synthesis of dyes and drugs.


a dibenzopyridine compound used in the synthesis of dyes and drugs. Its derivatives include fluorescent yellow dyes and the antiseptic agents acriflavine hydrochloride, acriflavine base, and proflavine.


A dye molecule capable of causing a FRAME-SHIFT MUTATION in DNA by interposing between adjacent base pairs. Acridine orange stains nucleic acid so that under ultraviolet light DNA appears green and RNA appears orange.

acridine (orange) (ak´ridēn),

n a dibenzopyridine compound used in the synthesis of dyes and drugs. In dentistry, has been used to research dental deposits.


a dibenzopyridine compound used in the synthesis of dyes and drugs. Derivatives of acridine are successful as antibacterial agents, finding their principal use as local antiseptics. They were popular at one time as antibabesial and trypanocidal agents. See also acriflavine, proflavine.

acridine orange stain
binds nonspecifically to nucleic acids, proteins, polysaccharides and glycosaminoglycans. Together with fluorescent microscopy, it is reportedly more sensitive than conventional staining methods for demonstrating Mycoplasma haemofelis in blood smears.
References in periodicals archive ?
The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides.
Amac: Bu calismanin amact varikoseli olan hastalarda sperm deoksiribontikleik asit (DNA) fragmantasyonunun saptanmast icin rutin ofis prosedurlerine ilaveten Acridine Orange (AO) kullaniminin arastirilmasidtr.
Since they are displaced by the float to the easily inspected twenty-nine micron free space surrounding the float, they can be visualized, by placing the centrifuged tube in a notched holder and examining the tube using a 50X oil objective on an epi-illuminating microscope, due to the parasites' uptake of acridine orange and the resultant fluorescence (14) (Figures 2 and 3).
These results indicate that acridine and dinitroaniline herbicides with the plant extracts are promising lead compounds for development as novel antileishmanial agents.
At least for ex vivo biopsy analysis, however, using exogenous nuclear stains, such as acridine orange, could largely circumvent this problem.
The solution of acridine orange dye (1 ml) is added.
Hemacolor stain (Harleco, a division of EM Industries, Inc) is useful for permanently stained smears of corneal scrapings, and fluorescent stains such as calcofluor white and acridine orange can be used to stain cytological specimens.
Acridine and acridone based compounds have been known for decades to exhibit a wide range of biological activities, including antibacterial, antimalarial, and antitumor activities.
Bacteria densities were determined by Acridine Orange Direct Counts (AODC) as previously described (3).
The difficulty of detecting intra-erythrocytic forms of babesia coupled with frequent low levels of parasitemia, may result in accurate diagnoses, although acridine orange and fluorescent microscopy may assist in the detection of parasites (1).