The case study documented the successful treatment of Acral Lentiginous Melanoma
on a 77-year-old woman with Tubercin.
The term acral lentiginous melanoma
(ALM), coined by Reed in 1976, applies to melanoma developing on palms, soles, and nail apparatus, which presents with clinical, histologic, and even biologic differences from melanoma developing elsewhere in the body.
2,5,9) For example, there is some evidence that nodular melanoma and acral lentiginous melanoma
have a worse prognosis than other subtypes.
While 1 study noted a possibly increased rate of S100-negative lesions among acral lentiginous melanomas
(34) and our study reports 2 S100-negative lesions arising in acral lentiginous or amelanotic melanomas, most of our S100-negative lesions arose in superficial spreading or nodular melanomas.