In non-white populations, acral
lentiginous melanoma constitutes 29% to 72% of all melanomas
A striking feature of this set of acral
spindle cell lesions is that the dermal spindle cells stain strongly for CD34 in all cases studied so far.
Where specific histological subtype was recorded, superficial spreading melanoma predominated with 47% cases, followed by nodular (20%), acral
lentiginous (11%) and lentigo maligna melanoma (9%).
Responding subjects include one patient with mucosal melanoma and one patient with acral
melanoma, two forms of melanoma that are particularly difficult to treat.
We present a 55-year-old male with anti-U1RNP positive limited cutaneous systemic sclerosis (lcSSc)/rheumatoid arthritis (RA) overlap syndrome, who developed acute-onset acral
ischemia leading to extensive gangrene.
Patients may have oral mucosal papillomas, sclerotic fibromas, and acral
keratotic papules, and are at risk for the development of adenocarcinoma of the breast, gastrointestinal tract, and thyroid.
In Western populations melanoma is largely cutaneous, while in China melanoma is mainly acral
distribution of MM was seen in 4 (57.1%) cases.
However after she decided to go for plastic surgery to try to sort it out she made the horrifying discovery she had acral
lentiginous subungual melanoma.
fibromyxoma (digital fibromyxoma) is a benign dermal fibroblastic neoplasm of acral
erythema, (2) a symmetric, painful erythema of the palms and soles with a prodrome of paresthesia and occasional bullous formation with desquamation upon resolution, is a rare side effect.
The last phenomena presents with recurrent crops of pustules in the acral
area, which is acropustulosis of infancy or postscabetic pustulosis.