acquired platelet function defect

Any non-hereditary defect in platelet function.

Clinical findings
Defective coagulation, easy bruising, bleeding gums, nosebleeds, vaginal bleeding, rectal bleeding, haematemesis, epistaxis, haematuria.

Aetiology
Polycythemia vera, leukaemia, myelofibrosis, renal failure, multiple myeloma, drugs—penicillins, salicylates, phenothiazines.

Diagnosis
Bleeding time, PT, PTT, platelet count.

acquired platelet function defect

Acquired qualitative platelet disorders Hematology Any non-hereditary defect in platelet function Etiology Polycythemia vera, leukemia, myelofibrosis, renal failure, multiple myeloma, drugs–penicillins, salicylates, phenothiazines Clinical Defective coagulation, easy bruising, bleeding gums, nosebleeds, vaginal bleeding, rectal bleeding, hematemesis, epistaxis, hematuria Diagnosis Bleeding time, PT, PTT, platelet count

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References in periodicals archive ?

Acquired platelet function defect may result from oxidative stress.

CD40 ligand and P-selectin in heterozygous Beta-thalassemia

In addition, no clinicians have specifically requested a platelet transfusion to correct an acquired platelet function defect in a patient undergoing a procedure.

Discontinuation of the bleeding time test without detectable adverse clinical impact