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com·mon var·i·a·ble im·mu·no·de·fi·cien·cy (CVI),[MIM*240500]
immunodeficiency of unknown cause, and usually unclassifiable; usual onset after age 15 years but may occur at any age in either sex; the total quantity of immunoglobulin is commonly less than 300 mg/dL; the number of B lymphocytes is often within normal limits but there is a lack of plasma cells in lymphoid tissue; cellular (T-lymphocyte) immunity is usually intact; there is an increased susceptibility to pyogenic sinopulmonary infection and often autoimmune disease.
Farlex Partner Medical Dictionary © Farlex 2012
Immunoglobulin deficiency caused by another illness, such as the loss of immunoglobulins in the urine in nephrotic syndrome, or in the stool, in patients with malabsorption.
See also: hypogammaglobulinemia
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